ENSGALG00000040729


Gallus gallus

Features
Gene ID: ENSGALG00000040729
  
Biological name :PIDD1
  
Synonyms : p53-induced death domain protein 1 / PIDD1
  
Possible biological names infered from orthology : p53-induced death domain-containing protein 1 / Q9ERV7 / Q9HB75
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 15787966
Gene end: 15800805
  
Corresponding Affymetrix probe sets: Gga.18226.1.S1_s_at (Chicken Array)   GgaAffx.9034.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045724
NCBI entrez gene - 426464     See in Manteia.
RefSeq - XM_004941462
swissprot - A0A1D5NZA7
Ensembl - ENSGALG00000040729
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pidd1ENSDARG00000074626Danio rerio
 PIDD1ENSG00000177595Homo sapiens
 Pidd1ENSMUSG00000025507Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRCH2 / leucine rich repeats and calponin homology domain containing 2 / Q3UMG5* / Q5VUJ6* / Leucine-rich repeat and calponin homology domain-containing protein 2 *ENSGALG0000000588214
LRCH1 / leucine rich repeats and calponin homology domain containing 1 / P62046* / Q9Y2L9* / Leucine-rich repeat and calponin homology domain-containing protein 1 *ENSGALG0000001699014
LRCH3 / leucine rich repeats and calponin homology domain containing 3 / Q8BVU0* / Q96II8* / Leucine-rich repeat and calponin homology domain-containing protein 3 *ENSGALG0000000759512
LRRC28 / leucine rich repeat containing 28 / Q3TX51* / Q86X40* / Leucine-rich repeat-containing protein 28 *ENSGALG000000070579
LRRC18 / leucine rich repeat containing 18 / Q8N456* / Q9CQ07* / Leucine-rich repeat-containing protein 18 *ENSGALG000000061689
LRRC57 / leucine rich repeat containing 57 / Q8N9N7* / leucine-rich repeat-containing protein 57 isoform a *ENSGALG000000091128
LRRC8B / leucine rich repeat containing 8 VRAC subunit B / Q5DU41* / Q6P9F7* / Volume-regulated anion channel subunit LRRC8B *ENSGALG000000061678
LRRC2 / leucine rich repeat containing 2 / Q9BYS8*ENSGALG000000136348
LRRC8D / leucine rich repeat containing 8 VRAC subunit D / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D *ENSGALG000000208057
LRRC8A / leucine rich repeat containing 8 VRAC subunit A / Q8IWT6* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A *ENSGALG000000045737
LRRC39 / leucine rich repeat containing 39 / Q8BGI7* / Q96DD0* / Leucine-rich repeat-containing protein 39 *ENSGALG000000052847
LRSAM1 / leucine rich repeat and sterile alpha motif containing 1 / Q6UWE0* / Q80ZI6* / E3 ubiquitin-protein ligase LRSAM1 *ENSGALG000000088197
LRRC8C / leucine rich repeat containing 8 VRAC subunit C / Q8R502* / Q8TDW0* / Volume-regulated anion channel subunit LRRC8C *ENSGALG000000061706
RSU1 / Ras suppressor protein 1 / Q15404*ENSGALG000000408915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000906  ZU5 domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR011029  Death-like domain superfamily
 IPR019502  Peptidase S68, pidd
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Caspase Activators and Caspases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017159 ATM / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction
 ENSGALG00000011297 CRADD / CASP2 and RIPK1 domain containing adaptor with death domain / O88843* / P78560* / Mus musculus CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), transcript varian...  / reaction / complex
 ENSGALG00000040729 PIDD1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *  / reaction / complex
 ENSGALG00000014698 CASP2 / caspase-2 / P29594* / P42575* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*  / reaction / complex






 

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