ENSGALG00000008819


Gallus gallus

Features
Gene ID: ENSGALG00000008819
  
Biological name :LRSAM1
  
Synonyms : leucine rich repeat and sterile alpha motif containing 1 / LRSAM1
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase LRSAM1 / Q6UWE0 / Q80ZI6
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 2026955
Gene end: 2051551
  
Corresponding Affymetrix probe sets: Gga.7897.1.S1_s_at (Chicken Array)   GgaAffx.22689.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014318
Ensembl peptide - ENSGALP00000051430
Ensembl peptide - ENSGALP00000048535
NCBI entrez gene - 417265     See in Manteia.
RefSeq - XM_015279652
RefSeq - XM_015279653
RefSeq - XM_015279654
RefSeq - XM_415540
swissprot - A0A1D5PF68
swissprot - A0A1D5P751
swissprot - E1BRU6
Ensembl - ENSGALG00000008819
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrsam1ENSDARG00000060683Danio rerio
 LRSAM1ENSG00000148356Homo sapiens
 Lrsam1ENSMUSG00000026792Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC8A / leucine rich repeat containing 8 VRAC subunit A / Q8IWT6* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A *ENSGALG0000000457313
LRRC8C / leucine rich repeat containing 8 VRAC subunit C / Q8R502* / Q8TDW0* / Volume-regulated anion channel subunit LRRC8C *ENSGALG0000000617013
LRRC8B / leucine rich repeat containing 8 VRAC subunit B / Q5DU41* / Q6P9F7* / Volume-regulated anion channel subunit LRRC8B *ENSGALG0000000616713
LRRC8D / leucine rich repeat containing 8 VRAC subunit D / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D *ENSGALG0000002080512
LRCH1 / leucine rich repeats and calponin homology domain containing 1 / P62046* / Q9Y2L9* / Leucine-rich repeat and calponin homology domain-containing protein 1 *ENSGALG0000001699010
LRCH2 / leucine rich repeats and calponin homology domain containing 2 / Q3UMG5* / Q5VUJ6* / Leucine-rich repeat and calponin homology domain-containing protein 2 *ENSGALG0000000588210
RSU1 / Ras suppressor protein 1 / Q15404*ENSGALG0000004089110
PIDD1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *ENSGALG000000407299
LRCH3 / leucine rich repeats and calponin homology domain containing 3 / Q8BVU0* / Q96II8* / Leucine-rich repeat and calponin homology domain-containing protein 3 *ENSGALG000000075958
LRRC28 / leucine rich repeat containing 28 / Q3TX51* / Q86X40* / Leucine-rich repeat-containing protein 28 *ENSGALG000000070578
LRRC39 / leucine rich repeat containing 39 / Q8BGI7* / Q96DD0* / Leucine-rich repeat-containing protein 39 *ENSGALG000000052847
LRRC2 / leucine rich repeat containing 2 / Q9BYS8*ENSGALG000000136347
LRRC57 / leucine rich repeat containing 57 / Q8N9N7* / leucine-rich repeat-containing protein 57 isoform a *ENSGALG000000091126
LRRC18 / leucine rich repeat containing 18 / Q8N456* / Q9CQ07* / Leucine-rich repeat-containing protein 18 *ENSGALG000000061686


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001660  Sterile alpha motif domain
 IPR001841  Zinc finger, RING-type
 IPR003591  Leucine-rich repeat, typical subtype
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030163 protein catabolic process IEA
 biological_processGO:0045806 negative regulation of endocytosis IEA
 biological_processGO:0046755 viral budding IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0070086 ubiquitin-dependent endocytosis IEA
 biological_processGO:1904417 positive regulation of xenophagy IEA
 biological_processGO:2000786 positive regulation of autophagosome assembly IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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