ENSGALG00000006167


Gallus gallus

Features
Gene ID: ENSGALG00000006167
  
Biological name :LRRC8B
  
Synonyms : leucine rich repeat containing 8 VRAC subunit B / LRRC8B
  
Possible biological names infered from orthology : Q5DU41 / Q6P9F7 / Volume-regulated anion channel subunit LRRC8B
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 15145067
Gene end: 15151080
  
Corresponding Affymetrix probe sets: GgaAffx.3849.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046339
Ensembl peptide - ENSGALP00000057275
Ensembl peptide - ENSGALP00000056970
Ensembl peptide - ENSGALP00000009943
NCBI entrez gene - 424516     See in Manteia.
RefSeq - XM_004936638
RefSeq - XM_015290645
swissprot - E1BZK2
swissprot - A0A1D5PWE4
Ensembl - ENSGALG00000006167
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRRC8BENSG00000197147Homo sapiens
 Lrrc8bENSMUSG00000070639Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC8A / leucine rich repeat containing 8 VRAC subunit A / Q8IWT6* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A *ENSGALG0000000457357
LRRC8C / leucine rich repeat containing 8 VRAC subunit C / Q8R502* / Q8TDW0* / Volume-regulated anion channel subunit LRRC8C *ENSGALG0000000617048
LRRC8D / leucine rich repeat containing 8 VRAC subunit D / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D *ENSGALG0000002080547
LRSAM1 / leucine rich repeat and sterile alpha motif containing 1 / Q6UWE0* / Q80ZI6* / E3 ubiquitin-protein ligase LRSAM1 *ENSGALG0000000881912
LRCH1 / leucine rich repeats and calponin homology domain containing 1 / P62046* / Q9Y2L9* / Leucine-rich repeat and calponin homology domain-containing protein 1 *ENSGALG000000169909
LRRC2 / leucine rich repeat containing 2 / Q9BYS8*ENSGALG000000136349
LRRC39 / leucine rich repeat containing 39 / Q8BGI7* / Q96DD0* / Leucine-rich repeat-containing protein 39 *ENSGALG000000052849
PIDD1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *ENSGALG000000407299
LRCH2 / leucine rich repeats and calponin homology domain containing 2 / Q3UMG5* / Q5VUJ6* / Leucine-rich repeat and calponin homology domain-containing protein 2 *ENSGALG000000058828
LRRC18 / leucine rich repeat containing 18 / Q8N456* / Q9CQ07* / Leucine-rich repeat-containing protein 18 *ENSGALG000000061687
LRCH3 / leucine rich repeats and calponin homology domain containing 3 / Q8BVU0* / Q96II8* / Leucine-rich repeat and calponin homology domain-containing protein 3 *ENSGALG000000075957
RSU1 / Ras suppressor protein 1 / Q15404*ENSGALG000000408917
LRRC28 / leucine rich repeat containing 28 / Q3TX51* / Q86X40* / Leucine-rich repeat-containing protein 28 *ENSGALG000000070576
LRRC57 / leucine rich repeat containing 57 / Q8N9N7* / leucine-rich repeat-containing protein 57 isoform a *ENSGALG000000091125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR021040  LRRC8, pannexin-like TM region
 IPR026906  Leucine rich repeat 5
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0098656 anion transmembrane transport IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034702 ion channel complex IBA
 molecular_functionGO:0005225 volume-sensitive anion channel activity IBA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004573 LRRC8A / leucine rich repeat containing 8 VRAC subunit A / Q8IWT6* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A *  / complex






 

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