ENSDARG00000103840


Danio rerio

Features
Gene ID: ENSDARG00000103840
  
Biological name :lrrc8db
  
Synonyms : leucine rich repeat containing 8 VRAC subunit Db / lrrc8db
  
Possible biological names infered from orthology : leucine rich repeat containing 8 VRAC subunit D / LRRC8D / Q7L1W4 / Q8BGR2 / Volume-regulated anion channel subunit LRRC8D
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 25167250
Gene end: 25189739
  
Corresponding Affymetrix probe sets: Dr.14977.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000139223
Ensembl peptide - ENSDARP00000154274
Ensembl peptide - ENSDARP00000135454
NCBI entrez gene - 563923     See in Manteia.
RefSeq - NM_001077380
RefSeq Peptide - NP_001070848
swissprot - A0A0R4IV88
swissprot - Q08BM6
ZFIN ID - ZDB-GENE-061013-487
Ensembl - ENSDARG00000103840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRRC8DENSGALG00000020805Gallus gallus
 LRRC8DENSG00000171492Homo sapiens
 Lrrc8dENSMUSG00000046079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrrc8da / leucine rich repeat containing 8 VRAC subunit Da / LRRC8D* / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D * / leucine rich repeat containing 8 VRAC subunit D*ENSDARG0000010337071
lrrc8ab / leucine rich repeat containing 8 VRAC subunit Ab / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...ENSDARG0000005215554
lrrc8aa / leucine rich repeat containing 8 VRAC subunit Aa / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...ENSDARG0000003218853
lrrc8c / leucine rich repeat containing 8 VRAC subunit C / Q8R502* / Q8TDW0* / Volume-regulated anion channel subunit LRRC8C *ENSDARG0000009991151
LRRC8E / si:zfos-323e3.4 / Q6NSJ5* / Q66JT1* / AC093423.3* / Volume-regulated anion channel subunit LRRC8E * / leucine rich repeat containing 8 VRAC subunit E*ENSDARG0000007828345
si:ch211-106h11.1ENSDARG0000001772042
lrsam1 / leucine rich repeat and sterile alpha motif containing 1 / Q6UWE0* / Q80ZI6* / E3 ubiquitin-protein ligase LRSAM1 *ENSDARG000000606839
lrch2 / leucine-rich repeats and calponin homology (CH) domain containing 2 / Q3UMG5* / Q5VUJ6* / leucine rich repeats and calponin homology domain containing 2* / Leucine-rich repeat and c...ENSDARG000000755808
F1R6I3 / lrrc39 / leucine rich repeat containing 39 / Q96DD0* / Q8BGI7* / Leucine-rich repeat-containing protein 39 *ENSDARG000000714658
lrch4 / leucine-rich repeats and calponin homology (CH) domain containing 4 / Q921G6* / O75427* / Gm20605* / predicted gene 20605* / leucine rich repeats and calponin homology domain contai...ENSDARG000000682588
lrch1 / leucine-rich repeats and calponin homology (CH) domain containing 1 / P62046* / Q9Y2L9* / leucine rich repeats and calponin homology domain containing 1* / Leucine-rich repeat and c...ENSDARG000000787788
lrrc28 / leucine rich repeat containing 28 / Q86X40*ENSDARG000000574777
rsu1 / Ras suppressor protein 1 / Q15404*ENSDARG000001028857
LRRC69 / si:ch73-302o18.2 / Q6ZNQ3* / Q9D9Q0* / leucine rich repeat containing 69* / Leucine-rich repeat-containing protein 69 *ENSDARG000000883166
pidd1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *ENSDARG000000746266
lrch3 / leucine-rich repeats and calponin homology (CH) domain containing 3 / Q8BVU0* / Q96II8* / leucine rich repeats and calponin homology domain containing 3* / Leucine-rich repeat and c...ENSDARG000001006796
lrrc18b / leucine rich repeat containing 18b / Q9CQ07* / LRRC18* / Q8N456* / leucine rich repeat containing 18* / Leucine-rich repeat-containing protein 18 *ENSDARG000000762366
si:dkey-1h4.4ENSDARG000001055486
lrrc18a / leucine rich repeat containing 18a / Q9CQ07* / LRRC18* / Q8N456* / leucine rich repeat containing 18* / Leucine-rich repeat-containing protein 18 *ENSDARG000000787905
lrrc57 / Q6DHL5 / leucine rich repeat containing 57 / Q8N9N7* / leucine-rich repeat-containing protein 57 isoform a *ENSDARG000000439384


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR021040  LRRC8, pannexin-like TM region
 IPR025875  Leucine rich repeat 4
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052155 lrrc8ab / leucine rich repeat containing 8 VRAC subunit Ab / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...  / complex






 

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