ENSDARG00000078283


Danio rerio

Features
Gene ID: ENSDARG00000078283
  
Biological name :LRRC8E
  
Synonyms : LRRC8E / si:zfos-323e3.4
  
Possible biological names infered from orthology : AC093423.3 / leucine rich repeat containing 8 VRAC subunit E / Q66JT1 / Q6NSJ5 / Volume-regulated anion channel subunit LRRC8E
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 124172
Gene end: 131401
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101717
Ensembl peptide - ENSDARP00000126191
NCBI entrez gene - 100333177     See in Manteia.
swissprot - E7FB32
ZFIN ID - ZDB-GENE-120215-44
Ensembl - ENSDARG00000078283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC093423.3ENSG00000271949Homo sapiens
 LRRC8EENSG00000171017Homo sapiens
 Lrrc8eENSMUSG00000046589Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrrc8c / leucine rich repeat containing 8 VRAC subunit C / Q8R502* / Q8TDW0* / Volume-regulated anion channel subunit LRRC8C *ENSDARG0000009991155
lrrc8aa / leucine rich repeat containing 8 VRAC subunit Aa / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...ENSDARG0000003218850
lrrc8ab / leucine rich repeat containing 8 VRAC subunit Ab / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...ENSDARG0000005215550
lrrc8db / leucine rich repeat containing 8 VRAC subunit Db / LRRC8D* / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D * / leucine rich repeat containing 8 VRAC subunit D*ENSDARG0000010384047
lrrc8da / leucine rich repeat containing 8 VRAC subunit Da / LRRC8D* / Q7L1W4* / Q8BGR2* / Volume-regulated anion channel subunit LRRC8D * / leucine rich repeat containing 8 VRAC subunit D*ENSDARG0000010337046
si:ch211-106h11.1ENSDARG0000001772039
lrsam1 / leucine rich repeat and sterile alpha motif containing 1 / Q6UWE0* / Q80ZI6* / E3 ubiquitin-protein ligase LRSAM1 *ENSDARG0000006068310
lrch1 / leucine-rich repeats and calponin homology (CH) domain containing 1 / P62046* / Q9Y2L9* / leucine rich repeats and calponin homology domain containing 1* / Leucine-rich repeat and c...ENSDARG000000787789
lrch4 / leucine-rich repeats and calponin homology (CH) domain containing 4 / Q921G6* / O75427* / Gm20605* / predicted gene 20605* / leucine rich repeats and calponin homology domain contai...ENSDARG000000682589
F1R6I3 / lrrc39 / leucine rich repeat containing 39 / Q96DD0* / Q8BGI7* / Leucine-rich repeat-containing protein 39 *ENSDARG000000714659
LRRC69 / si:ch73-302o18.2 / Q6ZNQ3* / Q9D9Q0* / leucine rich repeat containing 69* / Leucine-rich repeat-containing protein 69 *ENSDARG000000883168
lrch2 / leucine-rich repeats and calponin homology (CH) domain containing 2 / Q3UMG5* / Q5VUJ6* / leucine rich repeats and calponin homology domain containing 2* / Leucine-rich repeat and c...ENSDARG000000755808
lrrc28 / leucine rich repeat containing 28 / Q86X40*ENSDARG000000574778
pidd1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *ENSDARG000000746268
lrch3 / leucine-rich repeats and calponin homology (CH) domain containing 3 / Q8BVU0* / Q96II8* / leucine rich repeats and calponin homology domain containing 3* / Leucine-rich repeat and c...ENSDARG000001006797
rsu1 / Ras suppressor protein 1 / Q15404*ENSDARG000001028857
si:dkey-1h4.4ENSDARG000001055487
lrrc18b / leucine rich repeat containing 18b / Q9CQ07* / LRRC18* / Q8N456* / leucine rich repeat containing 18* / Leucine-rich repeat-containing protein 18 *ENSDARG000000762366
lrrc18a / leucine rich repeat containing 18a / Q9CQ07* / LRRC18* / Q8N456* / leucine rich repeat containing 18* / Leucine-rich repeat-containing protein 18 *ENSDARG000000787906
lrrc57 / Q6DHL5 / leucine rich repeat containing 57 / Q8N9N7* / leucine-rich repeat-containing protein 57 isoform a *ENSDARG000000439385


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR021040  LRRC8, pannexin-like TM region
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0098656 anion transmembrane transport IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034702 ion channel complex IBA
 molecular_functionGO:0005225 volume-sensitive anion channel activity IBA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052155 lrrc8ab / leucine rich repeat containing 8 VRAC subunit Ab / Q8IWT6* / LRRC8A* / Q80WG5* / Gm28035* / predicted gene, 28035* / Volume-regulated anion channel subunit LRRC8A * / leucine rich...  / complex






 

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