ENSMUSG00000046079


Mus musculus

Features
Gene ID: ENSMUSG00000046079
  
Biological name :Lrrc8d
  
Synonyms : Lrrc8d / Q8BGR2 / Volume-regulated anion channel subunit LRRC8D
  
Possible biological names infered from orthology : leucine rich repeat containing 8 VRAC subunit D / Q7L1W4
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: E5
Gene start: 105699969
Gene end: 105832436
  
Corresponding Affymetrix probe sets: 10523772 (MoGene1.0st)   10523778 (MoGene1.0st)   1433505_a_at (Mouse Genome 430 2.0 Array)   1433506_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117072
Ensembl peptide - ENSMUSP00000113603
Ensembl peptide - ENSMUSP00000114662
Ensembl peptide - ENSMUSP00000116346
Ensembl peptide - ENSMUSP00000057293
NCBI entrez gene - 231549     See in Manteia.
MGI - MGI:1922368
RefSeq - XM_011249436
RefSeq - NM_001122768
RefSeq - NM_178701
RefSeq - XM_006534893
RefSeq - XM_006534894
RefSeq - XM_006534895
RefSeq - XM_006534896
RefSeq Peptide - NP_001116240
RefSeq Peptide - NP_848816
swissprot - D3Z6C1
swissprot - D3Z5Q6
swissprot - Q8BGR2
swissprot - D3YV62
Ensembl - ENSMUSG00000046079
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc8daENSDARG00000103370Danio rerio
 lrrc8dbENSDARG00000103840Danio rerio
 LRRC8DENSGALG00000020805Gallus gallus
 LRRC8DENSG00000171492Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80WG5 / Gm28035 / predicted gene, 28035 / LRRC8A* / Q8IWT6* / leucine rich repeat containing 8 VRAC subunit A*ENSMUSG0000009904153
Lrrc8a / Q80WG5 / Volume-regulated anion channel subunit LRRC8A / Q8IWT6* / leucine rich repeat containing 8 VRAC subunit A*ENSMUSG0000000747653
Lrrc8c / Q8R502 / Volume-regulated anion channel subunit LRRC8C / Q8TDW0* / leucine rich repeat containing 8 VRAC subunit C*ENSMUSG0000005472049
Lrrc8e / Q66JT1 / Volume-regulated anion channel subunit LRRC8E / Q6NSJ5* / leucine rich repeat containing 8 VRAC subunit E*ENSMUSG0000004658947
Lrrc8b / Q5DU41 / Volume-regulated anion channel subunit LRRC8B / Q6P9F7* / leucine rich repeat containing 8 VRAC subunit B*ENSMUSG0000007063945
Lrsam1 / Q80ZI6 / E3 ubiquitin-protein ligase LRSAM1 / Q6UWE0* / leucine rich repeat and sterile alpha motif containing 1*ENSMUSG0000002679211
Lrch4 / Q921G6 / Leucine-rich repeat and calponin homology domain-containing protein 4 / O75427* / leucine rich repeats and calponin homology domain containing 4*ENSMUSG000000934459
Q921G6 / Gm20605 / predicted gene 20605 / LRCH4* / O75427* / leucine rich repeats and calponin homology domain containing 4*ENSMUSG000000297209
Lrch1 / P62046 / Leucine-rich repeat and calponin homology domain-containing protein 1 / Q9Y2L9* / leucine rich repeats and calponin homology domain containing 1*ENSMUSG000000680158
Lrch3 / Q8BVU0 / Leucine-rich repeat and calponin homology domain-containing protein 3 / Q96II8* / leucine rich repeats and calponin homology domain containing 3*ENSMUSG000000228018
Lrrc2 / leucine rich repeat containing 2 / Q9BYS8*ENSMUSG000000324958
Pidd1 / Q9ERV7 / p53-induced death domain-containing protein 1 / Q9HB75* / p53-induced death domain protein 1*ENSMUSG000000255078
Lrrc69 / Q9D9Q0 / Leucine-rich repeat-containing protein 69 / Q6ZNQ3* / leucine rich repeat containing 69*ENSMUSG000000231517
Lrch2 / Q3UMG5 / Leucine-rich repeat and calponin homology domain-containing protein 2 / Q5VUJ6* / leucine rich repeats and calponin homology domain containing 2*ENSMUSG000000312907
Lrrc28 / Q3TX51 / Leucine-rich repeat-containing protein 28 / Q86X40* / leucine rich repeat containing 28*ENSMUSG000000305567
Lrrc39 / Q8BGI7 / Leucine-rich repeat-containing protein 39 / Q96DD0* / leucine rich repeat containing 39*ENSMUSG000000279617
Rsu1 / Ras suppressor protein 1 / Q15404*ENSMUSG000000267276
Lrrc18 / Q9CQ07 / Leucine-rich repeat-containing protein 18 / Q8N456* / leucine rich repeat containing 18*ENSMUSG000000416735
Lrrc57 / leucine-rich repeat-containing protein 57 isoform a / Q8N9N7* / leucine rich repeat containing 57*ENSMUSG000000272864


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR021040  LRRC8, pannexin-like TM region
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034702 ion channel complex IBA
 molecular_functionGO:0005225 volume-sensitive anion channel activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000007476 Lrrc8a / Q80WG5 / Volume-regulated anion channel subunit LRRC8A / Q8IWT6* / leucine rich repeat containing 8 VRAC subunit A*  / complex






 

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