ENSMUSG00000099041


Mus musculus

Features
Gene ID: ENSMUSG00000099041
  
Biological name :Gm28035
  
Synonyms : Gm28035 / predicted gene, 28035 / Q80WG5
  
Possible biological names infered from orthology : leucine rich repeat containing 8 VRAC subunit A / LRRC8A / Q8IWT6
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 30240567
Gene end: 30282148
  
Corresponding Affymetrix probe sets: 10470954 (MoGene1.0st)   10470959 (MoGene1.0st)   1428394_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139038
MGI - MGI:5547771
swissprot - Q80WG5
Ensembl - ENSMUSG00000099041
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc8aaENSDARG00000032188Danio rerio
 lrrc8abENSDARG00000052155Danio rerio
 LRRC8AENSGALG00000004573Gallus gallus
 LRRC8AENSG00000136802Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lrrc8a / Q80WG5 / Volume-regulated anion channel subunit LRRC8A / Q8IWT6* / leucine rich repeat containing 8 VRAC subunit A*ENSMUSG00000007476100
Lrrc8b / Q5DU41 / Volume-regulated anion channel subunit LRRC8B / Q6P9F7* / leucine rich repeat containing 8 VRAC subunit B*ENSMUSG0000007063958
Lrrc8c / Q8R502 / Volume-regulated anion channel subunit LRRC8C / Q8TDW0* / leucine rich repeat containing 8 VRAC subunit C*ENSMUSG0000005472057
Lrrc8d / Q8BGR2 / Volume-regulated anion channel subunit LRRC8D / Q7L1W4* / leucine rich repeat containing 8 VRAC subunit D*ENSMUSG0000004607956
Lrrc8e / Q66JT1 / Volume-regulated anion channel subunit LRRC8E / Q6NSJ5* / leucine rich repeat containing 8 VRAC subunit E*ENSMUSG0000004658953
Lrsam1 / Q80ZI6 / E3 ubiquitin-protein ligase LRSAM1 / Q6UWE0* / leucine rich repeat and sterile alpha motif containing 1*ENSMUSG0000002679214
Lrch1 / P62046 / Leucine-rich repeat and calponin homology domain-containing protein 1 / Q9Y2L9* / leucine rich repeats and calponin homology domain containing 1*ENSMUSG0000006801510
Lrch4 / Q921G6 / Leucine-rich repeat and calponin homology domain-containing protein 4 / O75427* / leucine rich repeats and calponin homology domain containing 4*ENSMUSG0000009344510
Lrch3 / Q8BVU0 / Leucine-rich repeat and calponin homology domain-containing protein 3 / Q96II8* / leucine rich repeats and calponin homology domain containing 3*ENSMUSG0000002280110
Q921G6 / Gm20605 / predicted gene 20605 / LRCH4* / O75427* / leucine rich repeats and calponin homology domain containing 4*ENSMUSG0000002972010
Lrrc39 / Q8BGI7 / Leucine-rich repeat-containing protein 39 / Q96DD0* / leucine rich repeat containing 39*ENSMUSG000000279619
Lrrc69 / Q9D9Q0 / Leucine-rich repeat-containing protein 69 / Q6ZNQ3* / leucine rich repeat containing 69*ENSMUSG000000231519
Pidd1 / Q9ERV7 / p53-induced death domain-containing protein 1 / Q9HB75* / p53-induced death domain protein 1*ENSMUSG000000255079
Lrch2 / Q3UMG5 / Leucine-rich repeat and calponin homology domain-containing protein 2 / Q5VUJ6* / leucine rich repeats and calponin homology domain containing 2*ENSMUSG000000312908
Lrrc28 / Q3TX51 / Leucine-rich repeat-containing protein 28 / Q86X40* / leucine rich repeat containing 28*ENSMUSG000000305568
Lrrc2 / leucine rich repeat containing 2 / Q9BYS8*ENSMUSG000000324958
Rsu1 / Ras suppressor protein 1 / Q15404*ENSMUSG000000267277
Lrrc18 / Q9CQ07 / Leucine-rich repeat-containing protein 18 / Q8N456* / leucine rich repeat containing 18*ENSMUSG000000416736
Lrrc57 / leucine-rich repeat-containing protein 57 isoform a / Q8N9N7* / leucine rich repeat containing 57*ENSMUSG000000272865


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002329 pre-B cell differentiation IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport ISS
 biological_processGO:0006884 cell volume homeostasis ISS
 biological_processGO:0006970 response to osmotic stress ISS
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0098656 anion transmembrane transport IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034702 ion channel complex ISS
 molecular_functionGO:0005225 volume-sensitive anion channel activity ISO
 molecular_functionGO:0005253 anion channel activity ISO
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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