ENSMUSG00000093445


Mus musculus

Features
Gene ID: ENSMUSG00000093445
  
Biological name :Lrch4
  
Synonyms : Leucine-rich repeat and calponin homology domain-containing protein 4 / Lrch4 / Q921G6
  
Possible biological names infered from orthology : leucine rich repeats and calponin homology domain containing 4 / O75427
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 137629121
Gene end: 137641099
  
Corresponding Affymetrix probe sets: 10526656 (MoGene1.0st)   1424878_at (Mouse Genome 430 2.0 Array)   1451522_s_at (Mouse Genome 430 2.0 Array)   1454389_at (Mouse Genome 430 2.0 Array)   1454390_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135724
Ensembl peptide - ENSMUSP00000135832
Ensembl peptide - ENSMUSP00000031734
Ensembl peptide - ENSMUSP00000134767
Ensembl peptide - ENSMUSP00000135133
Ensembl peptide - ENSMUSP00000135242
Ensembl peptide - ENSMUSP00000135638
NCBI entrez gene - 231798     See in Manteia.
MGI - MGI:1917193
RefSeq - NM_001168652
RefSeq - NM_146164
RefSeq Peptide - NP_001162123
RefSeq Peptide - NP_666276
swissprot - Q921G6
swissprot - H3BIX9
swissprot - H3BJU9
swissprot - H3BK42
swissprot - H3BL36
swissprot - H3BLB4
swissprot - H3BLL3
Ensembl - ENSMUSG00000093445
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrch4ENSDARG00000068258Danio rerio
 LRCH4ENSG00000077454Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q921G6 / Gm20605 / predicted gene 20605 / LRCH4* / O75427* / leucine rich repeats and calponin homology domain containing 4*ENSMUSG00000029720100
Lrch3 / Q8BVU0 / Leucine-rich repeat and calponin homology domain-containing protein 3 / Q96II8* / leucine rich repeats and calponin homology domain containing 3*ENSMUSG0000002280144
Lrch1 / P62046 / Leucine-rich repeat and calponin homology domain-containing protein 1 / Q9Y2L9* / leucine rich repeats and calponin homology domain containing 1*ENSMUSG0000006801539
Lrch2 / Q3UMG5 / Leucine-rich repeat and calponin homology domain-containing protein 2 / Q5VUJ6* / leucine rich repeats and calponin homology domain containing 2*ENSMUSG0000003129037
Pidd1 / Q9ERV7 / p53-induced death domain-containing protein 1 / Q9HB75* / p53-induced death domain protein 1*ENSMUSG0000002550722
Lrrc28 / Q3TX51 / Leucine-rich repeat-containing protein 28 / Q86X40* / leucine rich repeat containing 28*ENSMUSG0000003055614
Lrrc69 / Q9D9Q0 / Leucine-rich repeat-containing protein 69 / Q6ZNQ3* / leucine rich repeat containing 69*ENSMUSG0000002315113
Lrsam1 / Q80ZI6 / E3 ubiquitin-protein ligase LRSAM1 / Q6UWE0* / leucine rich repeat and sterile alpha motif containing 1*ENSMUSG0000002679212
Lrrc8b / Q5DU41 / Volume-regulated anion channel subunit LRRC8B / Q6P9F7* / leucine rich repeat containing 8 VRAC subunit B*ENSMUSG0000007063912
Lrrc8c / Q8R502 / Volume-regulated anion channel subunit LRRC8C / Q8TDW0* / leucine rich repeat containing 8 VRAC subunit C*ENSMUSG0000005472011
Q80WG5 / Gm28035 / predicted gene, 28035 / LRRC8A* / Q8IWT6* / leucine rich repeat containing 8 VRAC subunit A*ENSMUSG0000009904111
Lrrc8e / Q66JT1 / Volume-regulated anion channel subunit LRRC8E / Q6NSJ5* / leucine rich repeat containing 8 VRAC subunit E*ENSMUSG0000004658911
Lrrc8a / Q80WG5 / Volume-regulated anion channel subunit LRRC8A / Q8IWT6* / leucine rich repeat containing 8 VRAC subunit A*ENSMUSG0000000747611
Lrrc8d / Q8BGR2 / Volume-regulated anion channel subunit LRRC8D / Q7L1W4* / leucine rich repeat containing 8 VRAC subunit D*ENSMUSG0000004607911
Lrrc2 / leucine rich repeat containing 2 / Q9BYS8*ENSMUSG0000003249510
Lrrc39 / Q8BGI7 / Leucine-rich repeat-containing protein 39 / Q96DD0* / leucine rich repeat containing 39*ENSMUSG0000002796110
Lrrc57 / leucine-rich repeat-containing protein 57 isoform a / Q8N9N7* / leucine rich repeat containing 57*ENSMUSG000000272869
Lrrc18 / Q9CQ07 / Leucine-rich repeat-containing protein 18 / Q8N456* / leucine rich repeat containing 18*ENSMUSG000000416739
Rsu1 / Ras suppressor protein 1 / Q15404*ENSMUSG000000267277


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001715  Calponin homology domain
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IBA
 cellular_componentGO:0016605 PML body ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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