ENSG00000077454


Homo sapiens

Features
Gene ID: ENSG00000077454
  
Biological name :LRCH4
  
Synonyms : leucine rich repeats and calponin homology domain containing 4 / LRCH4 / O75427
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q22.1
Gene start: 100574011
Gene end: 100586153
  
Corresponding Affymetrix probe sets: 221956_at (Human Genome U133 Plus 2.0 Array)   222017_x_at (Human Genome U133 Plus 2.0 Array)   90610_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419674
Ensembl peptide - ENSP00000483999
Ensembl peptide - ENSP00000419870
Ensembl peptide - ENSP00000309689
NCBI entrez gene - 4034     See in Manteia.
RefSeq - NM_002319
RefSeq - NM_001289934
RefSeq Peptide - NP_001276863
RefSeq Peptide - NP_002310
swissprot - O75427
swissprot - A0A087X197
swissprot - H7C5D9
swissprot - C9JYK0
Ensembl - ENSG00000077454
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrch4ENSDARG00000068258Danio rerio
 Lrch4ENSMUSG00000093445Mus musculus
 Q921G6ENSMUSG00000029720Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRCH1 / Q9Y2L9 / leucine rich repeats and calponin homology domain containing 1ENSG0000013614141
LRCH3 / Q96II8 / leucine rich repeats and calponin homology domain containing 3ENSG0000018600140
LRCH2 / Q5VUJ6 / leucine rich repeats and calponin homology domain containing 2ENSG0000013022436
PIDD1 / Q9HB75 / p53-induced death domain protein 1ENSG0000017759524
LRRC28 / Q86X40 / leucine rich repeat containing 28ENSG0000016890415
LRSAM1 / Q6UWE0 / leucine rich repeat and sterile alpha motif containing 1ENSG0000014835612
LRRC69 / Q6ZNQ3 / leucine rich repeat containing 69ENSG0000021495412
LRRC8E / Q6NSJ5 / leucine rich repeat containing 8 VRAC subunit EENSG0000017101711
LRRC8B / Q6P9F7 / leucine rich repeat containing 8 VRAC subunit BENSG0000019714711
LRRC8A / Q8IWT6 / leucine rich repeat containing 8 VRAC subunit AENSG0000013680211
LRRC2 / Q9BYS8 / leucine rich repeat containing 2ENSG0000016382711
LRRC8C / Q8TDW0 / leucine rich repeat containing 8 VRAC subunit CENSG0000017148810
LRRC8D / Q7L1W4 / leucine rich repeat containing 8 VRAC subunit DENSG0000017149210
LRRC39 / Q96DD0 / leucine rich repeat containing 39ENSG000001224779
LRRC57 / Q8N9N7 / leucine rich repeat containing 57ENSG000001809799
LRRC18 / Q8N456 / leucine rich repeat containing 18ENSG000001653839
RSU1 / Q15404 / Ras suppressor protein 1ENSG000001484847
AC093423.3ENSG000002719491


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001715  Calponin homology domain
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IBA
 cellular_componentGO:0016605 PML body IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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