ENSG00000136141


Homo sapiens

Features
Gene ID: ENSG00000136141
  
Biological name :LRCH1
  
Synonyms : leucine rich repeats and calponin homology domain containing 1 / LRCH1 / Q9Y2L9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q14.13
Gene start: 46553168
Gene end: 46753040
  
Corresponding Affymetrix probe sets: 214936_at (Human Genome U133 Plus 2.0 Array)   226795_at (Human Genome U133 Plus 2.0 Array)   235012_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419256
Ensembl peptide - ENSP00000374447
Ensembl peptide - ENSP00000374448
Ensembl peptide - ENSP00000417121
Ensembl peptide - ENSP00000308493
NCBI entrez gene - 23143     See in Manteia.
OMIM - 610368
RefSeq - XM_017020484
RefSeq - NM_001164211
RefSeq - NM_001164213
RefSeq - NM_015116
RefSeq - XM_017020483
RefSeq Peptide - NP_001157683
RefSeq Peptide - NP_001157685
RefSeq Peptide - NP_055931
swissprot - C9JWE0
swissprot - Q9Y2L9
swissprot - C9J5B8
Ensembl - ENSG00000136141
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrch1ENSDARG00000078778Danio rerio
 LRCH1ENSGALG00000016990Gallus gallus
 Lrch1ENSMUSG00000068015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRCH2 / Q5VUJ6 / leucine rich repeats and calponin homology domain containing 2ENSG0000013022444
LRCH3 / Q96II8 / leucine rich repeats and calponin homology domain containing 3ENSG0000018600137
LRCH4 / O75427 / leucine rich repeats and calponin homology domain containing 4ENSG0000007745437
PIDD1 / Q9HB75 / p53-induced death domain protein 1ENSG0000017759518
LRRC28 / Q86X40 / leucine rich repeat containing 28ENSG0000016890413
LRRC69 / Q6ZNQ3 / leucine rich repeat containing 69ENSG0000021495412
LRSAM1 / Q6UWE0 / leucine rich repeat and sterile alpha motif containing 1ENSG0000014835611
LRRC2 / Q9BYS8 / leucine rich repeat containing 2ENSG0000016382710
LRRC8A / Q8IWT6 / leucine rich repeat containing 8 VRAC subunit AENSG0000013680210
LRRC8E / Q6NSJ5 / leucine rich repeat containing 8 VRAC subunit EENSG0000017101710
LRRC8C / Q8TDW0 / leucine rich repeat containing 8 VRAC subunit CENSG000001714889
LRRC8D / Q7L1W4 / leucine rich repeat containing 8 VRAC subunit DENSG000001714929
LRRC8B / Q6P9F7 / leucine rich repeat containing 8 VRAC subunit BENSG000001971479
LRRC39 / Q96DD0 / leucine rich repeat containing 39ENSG000001224779
LRRC57 / Q8N9N7 / leucine rich repeat containing 57ENSG000001809798
LRRC18 / Q8N456 / leucine rich repeat containing 18ENSG000001653838
RSU1 / Q15404 / Ras suppressor protein 1ENSG000001484846
AC093423.3ENSG000002719491


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001715  Calponin homology domain
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:1990869 cellular response to chemokine IEA
 biological_processGO:2000405 negative regulation of T cell migration IEA
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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