ENSDARG00000029019


Danio rerio

Features
Gene ID: ENSDARG00000029019
  
Biological name :epb41b
  
Synonyms : epb41b / erythrocyte membrane protein band 4.1b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 26449615
Gene end: 26488169
  
Corresponding Affymetrix probe sets: Dr.3027.1.S1_at (Zebrafish Array)   NM_175084_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000039745
NCBI entrez gene - 326287     See in Manteia.
RefSeq - NM_175084
RefSeq Peptide - NP_778259
swissprot - Q8JG61
ZFIN ID - ZDB-GENE-030130-1
Ensembl - ENSDARG00000029019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPB41L2 / si:ch73-18b11.1 / O43491* / O70318* / erythrocyte membrane protein band 4.1 like 2* / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA.*ENSDARG0000009337416
epb41a / erythrocyte membrane protein band 4.1a / EPB41* / P48193* / P11171* / erythrocyte membrane protein band 4.1*ENSDARG0000009928316
epb41l3b / erythrocyte membrane protein band 4.1-like 3b / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000001991715
si:dkey-178k16.1 / Q9H4G0* / EPB41L1* / band 4.1-like protein 1 isoform d * / erythrocyte membrane protein band 4.1 like 1*ENSDARG0000007636415
epb41l3a / erythrocyte membrane protein band 4.1-like 3a / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000000225515
ptpn4a / protein tyrosine phosphatase, non-receptor type 4a / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000063113
ptpn4b / protein tyrosine phosphatase, non-receptor type 4b / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000018313
FRMD5 / si:ch211-69m14.1 / Q6P5H6* / Q7Z6J6* / FERM domain containing 5* / FERM domain-containing protein 5 *ENSDARG0000007594211
ptpn3 / protein tyrosine phosphatase, non-receptor type 3 / A2ALK8* / P26045*ENSDARG0000005578411
epb41l4a / erythrocyte membrane protein band 4.1 like 4A / P52963* / Q9HCS5* / Band 4.1-like protein 4A *ENSDARG0000004008711
frmd5 / FERM domain containing 5 / Q6P5H6* / Q7Z6J6* / FERM domain-containing protein 5 *ENSDARG0000007962210
frmd3 / FERM domain containing 3 / A2A2Y4* / Q8BHD4* / FERM domain-containing protein 3 *ENSDARG000000598859
epb41l4b / erythrocyte membrane protein band 4.1 like 4B / Q9H329* / Q9JMC8* / Band 4.1-like protein 4B *ENSDARG000000613988
epb41l5 / erythrocyte membrane protein band 4.1 like 5 / Q8BGS1* / Q9HCM4* / Band 4.1-like protein 5 *ENSDARG000000323248


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR007477  SAB domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 biological_processGO:0031032 actomyosin structure organization IBA
 biological_processGO:0035162 embryonic hemopoiesis IMP
 cellular_componentGO:0005856 cytoskeleton IBA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IDA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IDA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
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 ZFA:0000208 gall bladder gall bladder increased size , abnormal
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 ZFA:0000436 spleen spleen increased size , abnormal
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 ZFA:0000529 kidney kidney increased size , abnormal
kidney hyperplastic , abnormal
kidney nucleate erythrocyte apoptotic , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte broken , abnormal
nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte spherical , abnormal
nucleate erythrocyte immature , abnormal
nucleate erythrocyte increased fragility , abnormal
nucleate erythrocyte microtubule disorganized , abnormal
nucleate erythrocyte plasma membrane morphology , abnormal
nucleate erythrocyte cell projection membrane present , abnormal
nucleate erythrocyte binucleate , abnormal
nucleate erythrocyte nucleus condensed , abnormal
nucleate erythrocyte plasma membrane pointleted , abnormal
nucleate erythrocyte absent , abnormal
nucleate erythrocyte morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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