ENSDARG00000032324


Danio rerio

Features
Gene ID: ENSDARG00000032324
  
Biological name :epb41l5
  
Synonyms : epb41l5 / erythrocyte membrane protein band 4.1 like 5
  
Possible biological names infered from orthology : Band 4.1-like protein 5 / Q8BGS1 / Q9HCM4
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 28870357
Gene end: 28939796
  
Corresponding Affymetrix probe sets: Dr.3945.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000119020
Ensembl peptide - ENSDARP00000092050
Ensembl peptide - ENSDARP00000122986
Ensembl peptide - ENSDARP00000092043
NCBI entrez gene - 368449     See in Manteia.
RefSeq - NM_200089
RefSeq Peptide - NP_956383
swissprot - F1QVV9
swissprot - F1Q9F0
swissprot - F6NJ58
swissprot - Q6PNC5
ZFIN ID - ZDB-GENE-030616-450
Ensembl - ENSDARG00000032324
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EPB41L5ENSGALG00000011605Gallus gallus
 Q9HCM4ENSG00000115109Homo sapiens
 Q8BGS1ENSMUSG00000026383Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epb41l4b / erythrocyte membrane protein band 4.1 like 4B / Q9H329* / Q9JMC8* / Band 4.1-like protein 4B *ENSDARG0000006139852
EPB41L2 / si:ch73-18b11.1 / O43491* / O70318* / erythrocyte membrane protein band 4.1 like 2* / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA.*ENSDARG0000009337435
si:dkey-178k16.1 / Q9H4G0* / EPB41L1* / band 4.1-like protein 1 isoform d * / erythrocyte membrane protein band 4.1 like 1*ENSDARG0000007636433
epb41l4a / erythrocyte membrane protein band 4.1 like 4A / P52963* / Q9HCS5* / Band 4.1-like protein 4A *ENSDARG0000004008733
epb41l3a / erythrocyte membrane protein band 4.1-like 3a / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000000225532
epb41l3b / erythrocyte membrane protein band 4.1-like 3b / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000001991731
ptpn4b / protein tyrosine phosphatase, non-receptor type 4b / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000018331
FRMD5 / si:ch211-69m14.1 / Q6P5H6* / Q7Z6J6* / FERM domain containing 5* / FERM domain-containing protein 5 *ENSDARG0000007594230
ptpn4a / protein tyrosine phosphatase, non-receptor type 4a / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000063130
epb41a / erythrocyte membrane protein band 4.1a / EPB41* / P48193* / P11171* / erythrocyte membrane protein band 4.1*ENSDARG0000009928330
frmd5 / FERM domain containing 5 / Q6P5H6* / Q7Z6J6* / FERM domain-containing protein 5 *ENSDARG0000007962229
frmd3 / FERM domain containing 3 / A2A2Y4* / Q8BHD4* / FERM domain-containing protein 3 *ENSDARG0000005988528
epb41b / erythrocyte membrane protein band 4.1bENSDARG0000002901928
ptpn3 / protein tyrosine phosphatase, non-receptor type 3 / A2ALK8* / P26045*ENSDARG0000005578422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR030694  Band 4.1-like protein 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0021744 dorsal motor nucleus of vagus nerve development IMP
 biological_processGO:0031032 actomyosin structure organization IBA
 biological_processGO:0034629 cellular protein-containing complex localization IMP
 biological_processGO:0035088 establishment or maintenance of apical/basal cell polarity IMP
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IMP
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IMP
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEP
 biological_processGO:0048048 embryonic eye morphogenesis IMP
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IMP
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IMP
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000107 eye eye quality , abnormal
Show

 ZFA:0000112 gut gut decreased size , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
heart edematous , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer distributed , abnormal
Show

 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium patchy , abnormal
Show

 ZFA:0000151 pronephros pronephros quality , abnormal
Show

 ZFA:0000152 retina retina disorganized , abnormal
Show

 ZFA:0000161 third ventricle third ventricle absent , abnormal
third ventricle decreased volume , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000640 cornea cornea structure , abnormal
cornea anatomical surface structure , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
Show

 ZFA:0001135 neural tube neural tube neuroblast (sensu Vertebrata) mislocalised , abnormal
Show

 ZFA:0001331 outer limiting membrane outer limiting membrane aplastic , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer distributed , abnormal
Show

 ZFA:0001683 corneal epithelium corneal epithelium saccular , abnormal
corneal epithelium desmosome decreased amount , abnormal
Show

 ZFA:0001685 corneal stroma corneal stroma disorganized , abnormal
Show

 ZFA:0001695 dorsolateral motor nucleus of vagal nerve dorsolateral motor nucleus of vagal nerve malformed , abnormal
Show

 ZFA:0007067 vagal ganglion vagal ganglion fused with vagal ganglion , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell mislocalised , abnormal
retinal cone cell decreased amount , abnormal
Show

 ZFA:0009264 corneal epithelial cell corneal epithelial cell cellular adhesivity corneal epithelial cell , abnormal
Show

 ZFA:0009275 retinal rod cell retinal rod cell disorganized , abnormal
retinal rod cell increased distribution , abnormal
retinal rod cell mislocalised , abnormal
retinal rod cell deformed , abnormal
retinal rod cell decreased amount , abnormal
retinal rod cell photoreceptor outer segment decreased volume , abnormal
Show

 ZFA:0009280 Muller cell Muller cell mislocalised , abnormal
Muller cell decreased amount , abnormal
Show

 ZFA:0009306 neuroepithelial cell neuroepithelial cell centrosome mislocalised , abnormal
neuroepithelial cell cell-cell junction broken , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell disorganized , abnormal
retinal ganglion cell increased distribution , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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