ENSDARG00000055784


Danio rerio

Features
Gene ID: ENSDARG00000055784
  
Biological name :ptpn3
  
Synonyms : protein tyrosine phosphatase, non-receptor type 3 / ptpn3
  
Possible biological names infered from orthology : A2ALK8 / P26045
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 26547152
Gene end: 26600624
  
Corresponding Affymetrix probe sets: Dr.25452.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000118507
NCBI entrez gene - 407635     See in Manteia.
RefSeq - XM_682838
swissprot - F1QLN8
ZFIN ID - ZDB-GENE-030131-2934
Ensembl - ENSDARG00000055784
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011596Gallus gallus
 ENSGALG00000022909Gallus gallus
 PTPN3ENSG00000070159Homo sapiens
 Ptpn3ENSMUSG00000038764Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptpn4a / protein tyrosine phosphatase, non-receptor type 4a / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000063148
ptpn4b / protein tyrosine phosphatase, non-receptor type 4b / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000018346
epb41b / erythrocyte membrane protein band 4.1bENSDARG0000002901919
epb41a / erythrocyte membrane protein band 4.1a / EPB41* / P48193* / P11171* / erythrocyte membrane protein band 4.1*ENSDARG0000009928318
si:dkey-178k16.1 / Q9H4G0* / EPB41L1* / band 4.1-like protein 1 isoform d * / erythrocyte membrane protein band 4.1 like 1*ENSDARG0000007636417
EPB41L2 / si:ch73-18b11.1 / O43491* / O70318* / erythrocyte membrane protein band 4.1 like 2* / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA.*ENSDARG0000009337417
epb41l3a / erythrocyte membrane protein band 4.1-like 3a / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000000225517
epb41l3b / erythrocyte membrane protein band 4.1-like 3b / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000001991716
epb41l4a / erythrocyte membrane protein band 4.1 like 4A / P52963* / Q9HCS5* / Band 4.1-like protein 4A *ENSDARG0000004008714
FRMD5 / si:ch211-69m14.1 / Q6P5H6* / Q7Z6J6* / FERM domain containing 5* / FERM domain-containing protein 5 *ENSDARG0000007594213
frmd5 / FERM domain containing 5 / Q6P5H6* / Q7Z6J6* / FERM domain-containing protein 5 *ENSDARG0000007962213
epb41l5 / erythrocyte membrane protein band 4.1 like 5 / Q8BGS1* / Q9HCM4* / Band 4.1-like protein 5 *ENSDARG0000003232412
frmd3 / FERM domain containing 3 / A2A2Y4* / Q8BHD4* / FERM domain-containing protein 3 *ENSDARG0000005988511
epb41l4b / erythrocyte membrane protein band 4.1 like 4B / Q9H329* / Q9JMC8* / Band 4.1-like protein 4B *ENSDARG0000006139811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000299  FERM domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001478  PDZ domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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