ENSDARG00000000183


Danio rerio

Features
Gene ID: ENSDARG00000000183
  
Biological name :ptpn4b
  
Synonyms : protein tyrosine phosphatase, non-receptor type 4b / ptpn4b
  
Possible biological names infered from orthology : P29074 / protein tyrosine phosphatase, non-receptor type 4 / PTPN4 / Q9WU22 / Tyrosine-protein phosphatase non-receptor type 4
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 11778053
Gene end: 11833334
  
Corresponding Affymetrix probe sets: Dr.17284.1.A1_at (Zebrafish Array)   NM_001044313_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000000192
Ensembl peptide - ENSDARP00000105661
Ensembl peptide - ENSDARP00000112064
NCBI entrez gene - 407634     See in Manteia.
RefSeq - NM_001044313
RefSeq Peptide - NP_001037778
swissprot - F1QFY3
swissprot - Q1MTL1
swissprot - Q1MTL2
ZFIN ID - ZDB-GENE-030131-6259
Ensembl - ENSDARG00000000183
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPN4ENSG00000088179Homo sapiens
 Ptpn4ENSMUSG00000026384Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptpn4a / protein tyrosine phosphatase, non-receptor type 4a / PTPN4* / P29074* / Q9WU22* / protein tyrosine phosphatase, non-receptor type 4* / Tyrosine-protein phosphatase non-receptor type 4 *ENSDARG0000000063175
ptpn3 / protein tyrosine phosphatase, non-receptor type 3 / A2ALK8* / P26045*ENSDARG0000005578442
si:dkey-178k16.1 / Q9H4G0* / EPB41L1* / band 4.1-like protein 1 isoform d * / erythrocyte membrane protein band 4.1 like 1*ENSDARG0000007636422
EPB41L2 / si:ch73-18b11.1 / O43491* / O70318* / erythrocyte membrane protein band 4.1 like 2* / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA.*ENSDARG0000009337421
epb41a / erythrocyte membrane protein band 4.1a / EPB41* / P48193* / P11171* / erythrocyte membrane protein band 4.1*ENSDARG0000009928321
epb41b / erythrocyte membrane protein band 4.1bENSDARG0000002901921
epb41l3a / erythrocyte membrane protein band 4.1-like 3a / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000000225520
epb41l3b / erythrocyte membrane protein band 4.1-like 3b / Q9Y2J2* / EPB41L3* / erythrocyte membrane protein band 4.1 like 3*ENSDARG0000001991719
epb41l4a / erythrocyte membrane protein band 4.1 like 4A / P52963* / Q9HCS5* / Band 4.1-like protein 4A *ENSDARG0000004008718
frmd5 / FERM domain containing 5 / Q6P5H6* / Q7Z6J6* / FERM domain-containing protein 5 *ENSDARG0000007962215
FRMD5 / si:ch211-69m14.1 / Q6P5H6* / Q7Z6J6* / FERM domain containing 5* / FERM domain-containing protein 5 *ENSDARG0000007594215
epb41l5 / erythrocyte membrane protein band 4.1 like 5 / Q8BGS1* / Q9HCM4* / Band 4.1-like protein 5 *ENSDARG0000003232415
epb41l4b / erythrocyte membrane protein band 4.1 like 4B / Q9H329* / Q9JMC8* / Band 4.1-like protein 4B *ENSDARG0000006139814
frmd3 / FERM domain containing 3 / A2A2Y4* / Q8BHD4* / FERM domain-containing protein 3 *ENSDARG0000005988513


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000299  FERM domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR001478  PDZ domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR011993  PH-like domain superfamily
 IPR012151  Protein-tyrosine phosphatase, non-receptor type-3, -4
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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