ENSDARG00000030871


Danio rerio

Features
Gene ID: ENSDARG00000030871
  
Biological name :siah1
  
Synonyms : siah1 / siah E3 ubiquitin protein ligase 1
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase SIAH1A / P61092 / Q8IUQ4 / Siah1a / Siah1b / siah E3 ubiquitin protein ligase 1B
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 18439332
Gene end: 18472257
  
Corresponding Affymetrix probe sets: Dr.5064.1.S1_at (Zebrafish Array)   NM_199521_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000043842
Ensembl peptide - ENSDARP00000137095
NCBI entrez gene - 80955     See in Manteia.
RefSeq - NM_199521
RefSeq Peptide - NP_955815
swissprot - A0A0R4IPD0
swissprot - A0A0H2UKD5
ZFIN ID - ZDB-GENE-010319-31
Ensembl - ENSDARG00000030871
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIAH1ENSGALG00000003916Gallus gallus
 SIAH1ENSG00000196470Homo sapiens
 P61092ENSMUSG00000036840Mus musculus
 Siah1bENSMUSG00000040749Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
siah2l / seven in absentia homolog 2 (Drosophila)-like / SIAH2* / SIAH3* / Q06986* / O43255* / Q8IW03* / siah E3 ubiquitin protein ligase 2* / siah E3 ubiquitin protein ligase family member 3*ENSDARG0000004438176


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004162  E3 ubiquitin-protein ligase SIN-like
 IPR008974  TRAF-like
 IPR013010  Zinc finger, SIAH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018121  Seven-in-absentia protein, TRAF-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Netrin-1 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000022531 ntn1b / netrin 1b / NTN1* / O09118* / O95631* / netrin 1*  / complex / reaction
 ENSDARG00000105112 ntn1a / netrin 1a / NTN1* / O09118* / O95631* / netrin 1*  / complex / reaction






 

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