ENSMUSG00000040749


Mus musculus

Features
Gene ID: ENSMUSG00000040749
  
Biological name :Siah1b
  
Synonyms : Siah1b / siah E3 ubiquitin protein ligase 1B
  
Possible biological names infered from orthology : Q8IUQ4 / SIAH1 / siah E3 ubiquitin protein ligase 1
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F5
Gene start: 164070705
Gene end: 164076493
  
Corresponding Affymetrix probe sets: 10607747 (MoGene1.0st)   1419404_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071592
Ensembl peptide - ENSMUSP00000114867
Ensembl peptide - ENSMUSP00000043215
NCBI entrez gene - 20438     See in Manteia.
MGI - MGI:108063
RefSeq - NM_001308386
RefSeq - NM_009173
RefSeq - NM_001308385
RefSeq Peptide - NP_033199
RefSeq Peptide - NP_001295314
RefSeq Peptide - NP_001295315
swissprot - A2AHZ2
swissprot - A2AHZ3
Ensembl - ENSMUSG00000040749
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 siah1ENSDARG00000030871Danio rerio
 SIAH1ENSGALG00000003916Gallus gallus
 SIAH1ENSG00000196470Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Siah1a / P61092 / E3 ubiquitin-protein ligase SIAH1A / SIAH1* / Q8IUQ4* / siah E3 ubiquitin protein ligase 1*ENSMUSG0000003684098
Siah2 / Q06986 / siah E3 ubiquitin protein ligase 2 / O43255*ENSMUSG0000003643277
Siah3 / siah E3 ubiquitin protein ligase family member 3 / Q8IW03*ENSMUSG0000009172236


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004162  E3 ubiquitin-protein ligase SIN-like
 IPR008974  TRAF-like
 IPR013010  Zinc finger, SIAH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018121  Seven-in-absentia protein, TRAF-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Netrin-1 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000060534 Dcc / P70211 / Netrin receptor DCC / P43146* / DCC netrin 1 receptor*  / reaction / complex
 ENSMUSG00000020902 Ntn1 / O09118 / Netrin-1 / O95631*  / reaction / complex






 

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