ENSDARG00000032116


Danio rerio

Features
Gene ID: ENSDARG00000032116
  
Biological name :cnot7
  
Synonyms : CCR4-NOT transcription complex, subunit 7 / cnot7 / Q08BM8
  
Possible biological names infered from orthology : Q60809 / Q9UIV1
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 30413312
Gene end: 30425984
  
Corresponding Affymetrix probe sets: Dr.22156.1.A1_at (Zebrafish Array)   NM_001077255_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000113903
Ensembl peptide - ENSDARP00000156128
Ensembl peptide - ENSDARP00000087385
NCBI entrez gene - 768119     See in Manteia.
RefSeq - NM_001077255
RefSeq Peptide - NP_001070723
swissprot - E9QI08
swissprot - Q08BM8
ZFIN ID - ZDB-GENE-061013-29
Ensembl - ENSDARG00000032116
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNOT7ENSGALG00000013649Gallus gallus
 CNOT7ENSG00000198791Homo sapiens
 Cnot7ENSMUSG00000031601Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cnot8 / CCR4-NOT transcription complex, subunit 8 / Q9UFF9*ENSDARG0000002004379


Protein motifs (from Interpro)
Interpro ID Name
 IPR006941  Ribonuclease CAF1
 IPR012337  Ribonuclease H-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006402 mRNA catabolic process IMP
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0017148 negative regulation of translation IBA
 biological_processGO:0031047 gene silencing by RNA ISS
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay ISS
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ISS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ISS
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030014 CCR4-NOT complex ISS
 cellular_componentGO:0030015 CCR4-NOT core complex IBA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004532 exoribonuclease activity ISS
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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