ENSGALG00000013649


Gallus gallus

Features
Gene ID: ENSGALG00000013649
  
Biological name :CNOT7
  
Synonyms : CCR4-NOT transcription complex subunit 7 / CNOT7 / Q5ZJV9
  
Possible biological names infered from orthology : Q60809 / Q9UIV1
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 63562142
Gene end: 63581923
  
Corresponding Affymetrix probe sets: Gga.4905.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000022159
Ensembl peptide - ENSGALP00000051058
NCBI entrez gene - 422733     See in Manteia.
RefSeq - NM_001006454
RefSeq - XM_015285436
RefSeq Peptide - NP_001006454
swissprot - Q5ZJV9
Ensembl - ENSGALG00000013649
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnot7ENSDARG00000032116Danio rerio
 CNOT7ENSG00000198791Homo sapiens
 Cnot7ENSMUSG00000031601Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNOT8 / CCR4-NOT transcription complex subunit 8 / Q9D8X5* / Q9UFF9* / Mus musculus CCR4-NOT transcription complex, subunit 8 (Cnot8), transcript variant 2, mRNA.*ENSGALG0000000395075


Protein motifs (from Interpro)
Interpro ID Name
 IPR006941  Ribonuclease CAF1
 IPR012337  Ribonuclease H-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0017148 negative regulation of translation IBA
 biological_processGO:0031047 gene silencing by RNA ISS
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IEA
 biological_processGO:0042509 regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IEA
 biological_processGO:0061014 positive regulation of mRNA catabolic process IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030014 CCR4-NOT complex IEA
 cellular_componentGO:0030015 CCR4-NOT core complex IBA
 cellular_componentGO:0075341 host cell PML body IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IEA
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004532 exoribonuclease activity IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IBA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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