ENSGALG00000003950


Gallus gallus

Features
Gene ID: ENSGALG00000003950
  
Biological name :CNOT8
  
Synonyms : CCR4-NOT transcription complex subunit 8 / CNOT8
  
Possible biological names infered from orthology : Mus musculus CCR4-NOT transcription complex, subunit 8 (Cnot8), transcript variant 2, mRNA. / Q9D8X5 / Q9UFF9
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 12034550
Gene end: 12041047
  
Corresponding Affymetrix probe sets: GgaAffx.12278.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006287
Ensembl peptide - ENSGALP00000055218
Ensembl peptide - ENSGALP00000064058
NCBI entrez gene - 416255     See in Manteia.
RefSeq - XM_015293772
RefSeq - NM_001030618
RefSeq - XM_015293770
RefSeq - XM_015293771
RefSeq Peptide - NP_001025789
swissprot - Q5ZKA9
Ensembl - ENSGALG00000003950
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnot8ENSDARG00000020043Danio rerio
 CNOT8ENSG00000155508Homo sapiens
 Cnot8ENSMUSG00000020515Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNOT7 / Q5ZJV9 / CCR4-NOT transcription complex subunit 7 / Q60809* / Q9UIV1*ENSGALG0000001364973


Protein motifs (from Interpro)
Interpro ID Name
 IPR006941  Ribonuclease CAF1
 IPR012337  Ribonuclease H-like superfamily
 IPR027212  CCR4-NOT transcription complex subunit 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0017148 negative regulation of translation IBA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay IBA
 biological_processGO:0061014 positive regulation of mRNA catabolic process IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0030014 CCR4-NOT complex IEA
 cellular_componentGO:0030015 CCR4-NOT core complex IBA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IBA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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