ENSDARG00000035149


Danio rerio

Features
Gene ID: ENSDARG00000035149
  
Biological name :pex12
  
Synonyms : peroxisomal biogenesis factor 12 / pex12
  
Possible biological names infered from orthology : O00623 / Peroxisome assembly protein 12 / Q8VC48
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 61583655
Gene end: 61588998
  
Corresponding Affymetrix probe sets: Dr.12896.1.S1_at (Zebrafish Array)   Dr.20699.1.A1_s_at (Zebrafish Array)   NM_200205_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000050911
NCBI entrez gene - 393174     See in Manteia.
RefSeq - NM_200205
RefSeq Peptide - NP_956499
swissprot - B0R157
ZFIN ID - ZDB-GENE-040426-929
Ensembl - ENSDARG00000035149
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PEX12ENSGALG00000002151Gallus gallus
 PEX12ENSG00000108733Homo sapiens
 Pex12ENSMUSG00000018733Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006845  Pex, N-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017375  Peroxisome assembly protein 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006513 protein monoubiquitination IBA
 biological_processGO:0006625 protein targeting to peroxisome IEA
 biological_processGO:0016558 protein import into peroxisome matrix IBA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005779 integral component of peroxisomal membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:1990429 peroxisomal importomer complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004687 acaa1 / acetyl-CoA acyltransferase 1 / Q921H8* / Acaa1a* / Acaa1b* / P09110* / Q8VCH0* / acetyl-Coenzyme A acyltransferase 1B* / acetyl-Coenzyme A acyltransferase 1A*  / complex
 ENSDARG00000070654 pex5 / peroxisomal biogenesis factor 5 / O09012* / P50542* / Peroxisomal targeting signal 1 receptor *  / complex / reaction
 ENSDARG00000070958 pex6 / peroxisomal biogenesis factor 6 / Q13608* / Q99LC9* / Peroxisome assembly factor 2 *  / complex / reaction
 ENSDARG00000043484 ube2d2 / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) / P62838* / P62837* / Ube2d2a* / ubiquitin conjugating enzyme E2 D2* / ubiquitin-conjugating enzyme E2D 2A*  / reaction / complex
 ENSDARG00000028322 pex14 / peroxisomal biogenesis factor 14 / O75381* / Q9R0A0* / Peroxisomal membrane protein PEX14 *  / complex
 ENSDARG00000041511 pex10 / peroxisomal biogenesis factor 10 / B1AUE5* / O60683* / Peroxisome biosis factor 10 *  / complex
 ENSDARG00000098443 zfand6 / zinc finger, AN1-type domain 6 / Q6FIF0* / Q9DCH6* / zinc finger AN1-type containing 6*  / reaction / complex
 ENSDARG00000038576 ube2d1b / ubiquitin-conjugating enzyme E2D 1b / UBE2D1* / P51668* / P61080* / ubiquitin conjugating enzyme E2 D1*  / reaction / complex
 ENSDARG00000071037 pex13 / peroxisomal biogenesis factor 13 / Q92968* / Q9D0K1* / Peroxisomal membrane protein PEX13 *  / complex
 ENSDARG00000062421 pex2 / peroxisomal biogenesis factor 2 / P28328*  / complex
 ENSDARG00000042821 agps / alkylglycerone phosphate synthase / O00116*  / complex
 ENSDARG00000086740 phyh / phytanoyl-CoA 2-hydroxylase / O14832* / O35386* / phytanoyl-CoA hydroxylase*  / complex






 

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