ENSDARG00000039863


Danio rerio

Features
Gene ID: ENSDARG00000039863
  
Biological name :lifrb
  
Synonyms : leukemia inhibitory factor receptor alpha b / lifrb
  
Possible biological names infered from orthology : LIFR / LIF receptor alpha / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA. / P42702 / P42703
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 21244046
Gene end: 21261636
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000154113
Ensembl peptide - ENSDARP00000122803
Ensembl peptide - ENSDARP00000058305
NCBI entrez gene - 565104     See in Manteia.
RefSeq - NM_001113732
RefSeq - XM_009295324
RefSeq Peptide - NP_001107204
swissprot - F1QRJ3
swissprot - F1Q5F5
ZFIN ID - ZDB-GENE-080107-2
Ensembl - ENSDARG00000039863
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LIFRENSGALG00000003733Gallus gallus
 LIFRENSG00000113594Homo sapiens
 LifrENSMUSG00000054263Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lifra / leukemia inhibitory factor receptor alpha a / LIFR* / P42703* / P42702* / LIF receptor alpha* / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA.*ENSDARG0000009885726
osmr / oncostatin M receptorENSDARG0000010073815
il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *ENSDARG0000010469313
csf3r / colony stimulating factor 3 receptor (granulocyte) / Q99062* / colony stimulating factor 3 receptor*ENSDARG0000004595912
il12rb2l / interleukin 12 receptor, beta 2a, likeENSDARG0000007485012
il12rb2 / interleukin 12 receptor, beta 2a / P97378* / Q99665* / interleukin 12 receptor subunit beta 2*ENSDARG0000005215711


Protein motifs (from Interpro)
Interpro ID Name
 IPR003529  Long hematopoietin receptor, Gp130 family 2, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain hydrocephalic , abnormal
hindbrain axon decreased amount , abnormal
Show

 ZFA:0000445 optic tectum optic tectum axon decreased amount , abnormal
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 ZFA:0000453 cranial nerve X cranial nerve X mislocalised , abnormal
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 ZFA:0000664 cranial nerve VII cranial nerve VII decreased size , abnormal
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 ZFA:0000697 cranial nerve V cranial nerve V decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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