ENSDARG00000052157


Danio rerio

Features
Gene ID: ENSDARG00000052157
  
Biological name :il12rb2
  
Synonyms : il12rb2 / interleukin 12 receptor, beta 2a
  
Possible biological names infered from orthology : interleukin 12 receptor subunit beta 2 / P97378 / Q99665
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 34908597
Gene end: 34925690
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000005204
Ensembl peptide - ENSDARP00000123736
NCBI entrez gene - 100134971     See in Manteia.
RefSeq - NM_001113505
RefSeq Peptide - NP_001106977
swissprot - F8W5A3
swissprot - A8WH97
ZFIN ID - ZDB-GENE-080107-3
Ensembl - ENSDARG00000052157
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL12RB2ENSGALG00000011222Gallus gallus
 Q99665ENSG00000081985Homo sapiens
 P97378ENSMUSG00000018341Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *ENSDARG0000010469319
csf3r / colony stimulating factor 3 receptor (granulocyte) / Q99062* / colony stimulating factor 3 receptor*ENSDARG0000004595918
il12rb2l / interleukin 12 receptor, beta 2a, likeENSDARG0000007485015
lifra / leukemia inhibitory factor receptor alpha a / LIFR* / P42703* / P42702* / LIF receptor alpha* / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA.*ENSDARG0000009885715
osmr / oncostatin M receptorENSDARG0000010073813
lifrb / leukemia inhibitory factor receptor alpha b / LIFR* / P42703* / P42702* / LIF receptor alpha* / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA.*ENSDARG0000003986313


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Interleukin-35 Signalling
Interleukin-12 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex
 ENSDARG00000052157 il12rb2 / interleukin 12 receptor, beta 2a / P97378* / Q99665* / interleukin 12 receptor subunit beta 2*  / complex
 ENSDARG00000028731 stat4 / signal transducer and activator of transcription 4 / Q14765*  / complex
 ENSDARG00000018882 jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*  / complex
 ENSDARG00000104693 il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *  / complex
 ENSDARG00000076182 stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*  / complex
 ENSDARG00000020326 tyk2 / tyrosine kinase 2 / P29597*  / complex
 ENSDARG00000104808 jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*  / complex






 

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