ENSDARG00000045959


Danio rerio

Features
Gene ID: ENSDARG00000045959
  
Biological name :csf3r
  
Synonyms : colony stimulating factor 3 receptor (granulocyte) / csf3r
  
Possible biological names infered from orthology : colony stimulating factor 3 receptor / Granulocyte colony-stimulating factor receptor / P40223 / Q99062
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 3103182
Gene end: 3127749
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000063985
NCBI entrez gene - 100134935     See in Manteia.
RefSeq - XM_005173451
swissprot - F1R904
ZFIN ID - ZDB-GENE-080104-4
Ensembl - ENSDARG00000045959
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CSF3RENSGALG00000002112Gallus gallus
 CSF3RENSG00000119535Homo sapiens
 Csf3rENSMUSG00000028859Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *ENSDARG0000010469321
il12rb2 / interleukin 12 receptor, beta 2a / P97378* / Q99665* / interleukin 12 receptor subunit beta 2*ENSDARG0000005215718
il12rb2l / interleukin 12 receptor, beta 2a, likeENSDARG0000007485015
lifra / leukemia inhibitory factor receptor alpha a / LIFR* / P42703* / P42702* / LIF receptor alpha* / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA.*ENSDARG0000009885715
lifrb / leukemia inhibitory factor receptor alpha b / LIFR* / P42703* / P42702* / LIF receptor alpha* / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA.*ENSDARG0000003986314
osmr / oncostatin M receptorENSDARG0000010073812


Protein motifs (from Interpro)
Interpro ID Name
 IPR003529  Long hematopoietin receptor, Gp130 family 2, conserved site
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR010457  Immunoglobulin C2-set-like, ligand-binding
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0030099 myeloid cell differentiation IMP
 biological_processGO:0030223 neutrophil differentiation IMP
 biological_processGO:0030224 monocyte differentiation IMP
 biological_processGO:0030225 macrophage differentiation IMP
 biological_processGO:0030851 granulocyte differentiation IMP
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0060216 definitive hemopoiesis IMP
 biological_processGO:1901532 regulation of hematopoietic progenitor cell differentiation IGI
 biological_processGO:1901534 positive regulation of hematopoietic progenitor cell differentiation IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0000123 liver liver neutrophil decreased amount , abnormal
liver neutrophil amount , ameliorated
liver size , ameliorated
liver macrophage increased amount , abnormal
Show

 ZFA:0000669 head kidney head kidney myeloid cell decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , abnormal
whole organism has fewer parts of type neutrophil , abnormal
Show

 ZFA:0001115 trunk trunk neutrophil decreased amount , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic multipotent progenitor cell increased amount , abnormal
Show

 ZFA:0005029 rostral blood island rostral blood island neutrophil decreased amount , abnormal
rostral blood island mononuclear phagocyte aggregated , abnormal
rostral blood island mononuclear phagocyte decreased amount , abnormal
Show

 ZFA:0009048 granulocyte granulocyte decreased amount , abnormal
Show

 ZFA:0009141 macrophage macrophage decreased amount , abnormal
macrophage increased amount , abnormal
macrophage amount , ameliorated
Show

 ZFA:0009159 mucus secreting cell mucus secreting cell decreased amount , abnormal
mucus secreting cell proliferative , abnormal
Show

 ZFA:0009309 leukocyte leukocyte aggregated , abnormal
leukocyte decreased amount , abnormal
Show

 ZFA:0009324 myeloid cell myeloid cell aggregated , abnormal
myeloid cell decreased amount , abnormal
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
neutrophil increased amount , abnormal
neutrophil absent , abnormal
neutrophil decreased distribution , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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