ENSDARG00000041068


Danio rerio

Features
Gene ID: ENSDARG00000041068
  
Biological name :got2a
  
Synonyms : glutamic-oxaloacetic transaminase 2a, mitochondrial / got2a
  
Possible biological names infered from orthology : glutamatic-oxaloacetic transaminase 2, mitochondrial / glutamic-oxaloacetic transaminase 2 / GOT2 / P00505 / P05202
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 21178721
Gene end: 21188768
  
Corresponding Affymetrix probe sets: Dr.1544.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000060165
NCBI entrez gene - 406688     See in Manteia.
swissprot - Q7SYK7
ZFIN ID - ZDB-GENE-040426-2703
Ensembl - ENSDARG00000041068
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GOT2ENSGALG00000002321Gallus gallus
 GOT2ENSG00000125166Homo sapiens
 Got2ENSMUSG00000031672Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
got2b / glutamic-oxaloacetic transaminase 2b, mitochondrial / GOT2* / P00505* / P05202* / glutamic-oxaloacetic transaminase 2* / glutamatic-oxaloacetic transaminase 2, mitochondrial*ENSDARG0000000584085
got1 / glutamic-oxaloacetic transaminase 1, soluble / P05201* / P17174* / glutamic-oxaloacetic transaminase 1*ENSDARG0000003909345
got1l1 / glutamic-oxaloacetic transaminase 1 like 1 / Q7TSV6* / Q8NHS2*ENSDARG0000005364432


Protein motifs (from Interpro)
Interpro ID Name
 IPR000796  Aspartate/other aminotransferase
 IPR004838  Aminotransferases, class-I, pyridoxal-phosphate-binding site
 IPR004839  Aminotransferase, class I/classII
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0006533 aspartate catabolic process IBA
 biological_processGO:0009058 biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity IEA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Gluconeogenesis
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000005840 got2b / glutamic-oxaloacetic transaminase 2b, mitochondrial / GOT2* / P00505* / P05202* / glutamic-oxaloacetic transaminase 2* / glutamatic-oxaloacetic transaminase 2, mitochondrial*  / complex
 ENSDARG00000041068 got2a / glutamic-oxaloacetic transaminase 2a, mitochondrial / GOT2* / P00505* / P05202* / glutamic-oxaloacetic transaminase 2* / glutamatic-oxaloacetic transaminase 2, mitochondrial*  / complex






 

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