ENSMUSG00000031672


Mus musculus

Features
Gene ID: ENSMUSG00000031672
  
Biological name :Got2
  
Synonyms : glutamatic-oxaloacetic transaminase 2, mitochondrial / Got2 / P05202
  
Possible biological names infered from orthology : glutamic-oxaloacetic transaminase 2 / P00505
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: D1
Gene start: 95864134
Gene end: 95888547
  
Corresponding Affymetrix probe sets: 10535025 (MoGene1.0st)   10580969 (MoGene1.0st)   1417715_a_at (Mouse Genome 430 2.0 Array)   1417716_at (Mouse Genome 430 2.0 Array)   1430397_at (Mouse Genome 430 2.0 Array)   1438537_at (Mouse Genome 430 2.0 Array)   1447768_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034097
NCBI entrez gene - 14719     See in Manteia.
MGI - MGI:95792
RefSeq - NM_010325
RefSeq Peptide - NP_034455
swissprot - P05202
Ensembl - ENSMUSG00000031672
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 got2aENSDARG00000041068Danio rerio
 got2bENSDARG00000005840Danio rerio
 GOT2ENSGALG00000002321Gallus gallus
 GOT2ENSG00000125166Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Got1 / P05201 / glutamic-oxaloacetic transaminase 1, soluble / P17174* / glutamic-oxaloacetic transaminase 1*ENSMUSG0000002519044
Got1l1 / Q7TSV6 / glutamic-oxaloacetic transaminase 1-like 1 / Q8NHS2*ENSMUSG0000003972027


Protein motifs (from Interpro)
Interpro ID Name
 IPR000796  Aspartate/other aminotransferase
 IPR004838  Aminotransferases, class-I, pyridoxal-phosphate-binding site
 IPR004839  Aminotransferase, class I/classII
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006103 2-oxoglutarate metabolic process ISS
 biological_processGO:0006107 oxaloacetate metabolic process IDA
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0006531 aspartate metabolic process IEA
 biological_processGO:0006532 aspartate biosynthetic process IDA
 biological_processGO:0006533 aspartate catabolic process IEA
 biological_processGO:0006536 glutamate metabolic process ISS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0019550 glutamate catabolic process to aspartate IDA
 biological_processGO:0019551 glutamate catabolic process to 2-oxoglutarate IDA
 biological_processGO:0043648 dicarboxylic acid metabolic process IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0097052 L-kynurenine metabolic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0043209 myelin sheath IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity ISO
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016212 kynurenine-oxoglutarate transaminase activity IEA
 molecular_functionGO:0016597 amino acid binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0031406 carboxylic acid binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Gluconeogenesis
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031672 Got2 / P05202 / glutamatic-oxaloacetic transaminase 2, mitochondrial / P00505* / glutamic-oxaloacetic transaminase 2*  / complex






 

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