ENSMUSG00000025190


Mus musculus

Features
Gene ID: ENSMUSG00000025190
  
Biological name :Got1
  
Synonyms : glutamic-oxaloacetic transaminase 1, soluble / Got1 / P05201
  
Possible biological names infered from orthology : glutamic-oxaloacetic transaminase 1 / P17174
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 43499752
Gene end: 43524605
  
Corresponding Affymetrix probe sets: 10467842 (MoGene1.0st)   1450970_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026196
Ensembl peptide - ENSMUSP00000117986
NCBI entrez gene - 14718     See in Manteia.
MGI - MGI:95791
RefSeq - NM_010324
RefSeq Peptide - NP_034454
swissprot - F7ALS6
swissprot - P05201
Ensembl - ENSMUSG00000025190
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 got1ENSDARG00000039093Danio rerio
 GOT1ENSGALG00000007484Gallus gallus
 GOT1ENSG00000120053Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Got2 / P05202 / glutamatic-oxaloacetic transaminase 2, mitochondrial / P00505* / glutamic-oxaloacetic transaminase 2*ENSMUSG0000003167246
Got1l1 / Q7TSV6 / glutamic-oxaloacetic transaminase 1-like 1 / Q8NHS2*ENSMUSG0000003972040


Protein motifs (from Interpro)
Interpro ID Name
 IPR000796  Aspartate/other aminotransferase
 IPR004838  Aminotransferases, class-I, pyridoxal-phosphate-binding site
 IPR004839  Aminotransferase, class I/classII
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006103 2-oxoglutarate metabolic process ISS
 biological_processGO:0006107 oxaloacetate metabolic process IDA
 biological_processGO:0006114 glycerol biosynthetic process IDA
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0006531 aspartate metabolic process IEA
 biological_processGO:0006532 aspartate biosynthetic process IDA
 biological_processGO:0006533 aspartate catabolic process IEA
 biological_processGO:0006536 glutamate metabolic process ISS
 biological_processGO:0007219 Notch signaling pathway IDA
 biological_processGO:0008652 cellular amino acid biosynthetic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0019550 glutamate catabolic process to aspartate IDA
 biological_processGO:0019551 glutamate catabolic process to 2-oxoglutarate IDA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0043648 dicarboxylic acid metabolic process IEA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0055089 fatty acid homeostasis IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity ISO
 molecular_functionGO:0004609 phosphatidylserine decarboxylase activity IDA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0031406 carboxylic acid binding IEA
 molecular_functionGO:0047801 L-cysteine:2-oxoglutarate aminotransferase activity ISS


Pathways (from Reactome)
Pathway description
Gluconeogenesis
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025190 Got1 / P05201 / glutamic-oxaloacetic transaminase 1, soluble / P17174* / glutamic-oxaloacetic transaminase 1*  / complex






 

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