ENSDARG00000041481


Danio rerio

Features
Gene ID: ENSDARG00000041481
  
Biological name :smg5
  
Synonyms : smg5 / SMG5 nonsense mediated mRNA decay factor
  
Possible biological names infered from orthology : Protein SMG5 / Q6ZPY2 / Q9UPR3
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 45693413
Gene end: 45734213
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000060808
NCBI entrez gene - 553261     See in Manteia.
RefSeq - NM_001024923
RefSeq Peptide - NP_001020094
swissprot - F1R7R1
ZFIN ID - ZDB-GENE-050913-144
Ensembl - ENSDARG00000041481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMG5ENSGALG00000029918Gallus gallus
 SMG5ENSG00000198952Homo sapiens
 Smg5ENSMUSG00000001415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smg6 / SMG6 nonsense mediated mRNA decay factor / P61406* / Q86US8* / Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)*ENSDARG0000010048116
smg7 / SMG7 nonsense mediated mRNA decay factor / Q5RJH6* / Q92540* / Protein SMG7 *ENSDARG0000006076712


Protein motifs (from Interpro)
Interpro ID Name
 IPR002716  PIN domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR018834  DNA/RNA-binding domain, Est1-type
 IPR019458  Telomerase activating protein Est1
 IPR029060  PIN-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0007004 telomere maintenance via telomerase IBA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0043487 regulation of RNA stability IBA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005697 telomerase holoenzyme complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004540 ribonuclease activity IBA
 molecular_functionGO:0042162 telomeric DNA binding IBA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IBA
 molecular_functionGO:0070034 telomerase RNA binding IBA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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