ENSDARG00000042707


Danio rerio

Features
Gene ID: ENSDARG00000042707
  
Biological name :cx30.3
  
Synonyms : connexin 30.3 / cx30.3
  
Possible biological names infered from orthology : gap junction protein beta 2 / gap junction protein beta 6 / GJB2 / GJB6 / O95452 / P29033 / P70689 / Q00977
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 21401189
Gene end: 21405066
  
Corresponding Affymetrix probe sets: DrAffx.1.65.S1_at (Zebrafish Array)   NM_212825_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062668
Ensembl peptide - ENSDARP00000112290
NCBI entrez gene - 404725     See in Manteia.
RefSeq - NM_212825
RefSeq Peptide - NP_997990
swissprot - Q503F4
ZFIN ID - ZDB-GENE-040406-1
Ensembl - ENSDARG00000042707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GJB2ENSGALG00000022720Gallus gallus
 GJB6ENSGALG00000017136Gallus gallus
 GJB2ENSG00000165474Homo sapiens
 GJB6ENSG00000121742Homo sapiens
 Gjb2ENSMUSG00000046352Mus musculus
 Gjb6ENSMUSG00000040055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cx31.7 / connexin 31.7 / GJB1* / P28230* / P08034* / gap junction protein beta 1*ENSDARG0000005806452
cx27.5 / connexin 27.5 / GJB1* / P28230* / P08034* / gap junction protein beta 1*ENSDARG0000003555351
cx35.4 / connexin 35.4 / GJB3* / P28231* / O75712* / gap junction protein beta 3*ENSDARG0000004286646
cx34.4 / connexin 34.4 / GJB4* / GJB5* / Q9NTQ9* / O95377* / Q02738* / Q02739* / gap junction protein beta 4* / gap junction protein beta 5*ENSDARG0000007585445
cx30.9 / connexin 30.9ENSDARG0000007036242
cx28.6 / connexin 28.6ENSDARG0000000392541
cx28.8 / connexin 28.8 / GJB7* / Q6PEY0* / gap junction protein beta 7*ENSDARG0000007104240
GJD4 / gap junction protein delta 4 / Q96KN9*ENSDARG0000011689530


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005243 gap junction channel activity IDA


Pathways (from Reactome)
Pathway description
Transport of connexons to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000530 lapillus lapillus decreased width , abnormal
lapillus adjacent to sagitta , abnormal
Show

 ZFA:0000676 sagitta sagitta decreased width , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042707 cx30.3 / connexin 30.3 / GJB2* / GJB6* / Q00977* / O95452* / P29033* / P70689* / gap junction protein beta 2* / gap junction protein beta 6*  / complex






 

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