ENSDARG00000042993


Danio rerio

Features
Gene ID: ENSDARG00000042993
  
Biological name :prss1
  
Synonyms : protease, serine 1 / prss1
  
Possible biological names infered from orthology : 1810009J06Rik / 2210010C04Rik / Gm10334 / Gm2663 / Gm4744 / Gm5771 / P07146 / P07477 / P07478 / P35030 / protease, serine 2 / PRSS2 / PRSS3 / RIKEN cDNA 1810009J06 gene / RIKEN cDNA 2210010C04 gene / serine protease 1 / serine protease 2 / serine protease 3 / Try10 / Try4 / Try5 / trypsin 10 / trypsin 4
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 25080764
Gene end: 25085327
  
Corresponding Affymetrix probe sets: Dr.20934.1.S1_at (Zebrafish Array)   NM_131708_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072127
NCBI entrez gene - 65223     See in Manteia.
RefSeq - NM_131708
RefSeq Peptide - NP_571783
swissprot - Q561Z7
ZFIN ID - ZDB-GENE-010131-7
Ensembl - ENSDARG00000042993
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000040609Gallus gallus
 ENSGALG00000030650Gallus gallus
 ENSGALG00000027291Gallus gallus
 PRSS2ENSGALG00000032796Gallus gallus
 PRSS1ENSG00000204983Homo sapiens
 PRSS2ENSG00000275896Homo sapiens
 PRSS3ENSG00000010438Homo sapiens
 1810009J06RikENSMUSG00000094808Mus musculus
 2210010C04RikENSMUSG00000029882Mus musculus
 Gm10334ENSMUSG00000071517Mus musculus
 Gm2663ENSMUSG00000096525Mus musculus
 Gm4744ENSMUSG00000063252Mus musculus
 Gm5771ENSMUSG00000058119Mus musculus
 Prss1ENSMUSG00000062751Mus musculus
 Prss2ENSMUSG00000057163Mus musculus
 Prss3ENSMUSG00000071519Mus musculus
 Try10ENSMUSG00000071521Mus musculus
 Try4ENSMUSG00000054106Mus musculus
 Try5ENSMUSG00000036938Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prss59.1 / protease, serine, 59, tandem duplicate 1ENSDARG0000007927464
prss59.2 / protease, serine, 59, tandem duplicate 2ENSDARG0000007374264
zgc:92590ENSDARG0000004028257
zgc:171509ENSDARG0000006830350
CU062628.1ENSDARG0000009026748
si:dkey-33m11.7ENSDARG0000005501142
AL954146.1ENSDARG0000003889142
zmp:0000001088ENSDARG0000011645741
si:dkey-33m11.8ENSDARG0000005501439


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Activation of Matrix Metalloproteinases
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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