Manteia

ENSMUSG00000057163

Mus musculus

Features

Gene ID:	ENSMUSG00000057163

Biological name :	Prss2

Synonyms :	P07146 / protease, serine 2 / Prss2

Possible biological names infered from orthology :	P07477 / P07478 / P35030 / PRSS1 / PRSS3 / serine protease 1 / serine protease 2 / serine protease 3

Species:	Mus musculus

Chr. number:	6
Strand:	1
Band:	B1
Gene start:	41521787
Gene end:	41525079

Corresponding Affymetrix probe sets:	10537627 (MoGene1.0st) 1417682_a_at (Mouse Genome 430 2.0 Array) 1433459_x_at (Mouse Genome 430 2.0 Array) 1433573_x_at (Mouse Genome 430 2.0 Array) 1435507_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000065393 NCBI entrez gene - 22072 See in Manteia. MGI - MGI:102759 RefSeq - NM_009430 RefSeq Peptide - NP_033456 swissprot - P07146 swissprot - Q792Y6 Ensembl - ENSMUSG00000057163

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
prss1	ENSDARG00000042993	Danio rerio
	ENSGALG00000027291	Gallus gallus
	ENSGALG00000030650	Gallus gallus
	ENSGALG00000040609	Gallus gallus
PRSS2	ENSGALG00000032796	Gallus gallus
PRSS1	ENSG00000204983	Homo sapiens
PRSS2	ENSG00000275896	Homo sapiens
PRSS3	ENSG00000010438	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Try4 / trypsin 4 / PRSS3* / PRSS1* / PRSS2* / P35030* / P07478* / P07477* / serine protease 3* / serine protease 1* / serine protease 2*	ENSMUSG00000054106	91
Try5 / PRSS2* / PRSS3* / PRSS1* / P07477* / P35030* / P07478* / serine protease 2* / serine protease 3* / serine protease 1*	ENSMUSG00000036938	90
Prss1 / PRSS2* / PRSS3* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*	ENSMUSG00000062751	89
Try10 / trypsin 10 / PRSS3* / PRSS1* / PRSS2* / P35030* / P07478* / P07477* / serine protease 3* / serine protease 1* / serine protease 2*	ENSMUSG00000071521	89
Prss3 / PRSS2* / PRSS1* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*	ENSMUSG00000071519	88
Gm5771 / PRSS1* / PRSS2* / PRSS3* / P07477* / P07478* / P35030* / serine protease 2* / serine protease 3* / serine protease 1*	ENSMUSG00000058119	88
Gm10334 / PRSS1* / PRSS2* / PRSS3* / P07477* / P07478* / P35030* / serine protease 2* / serine protease 3* / serine protease 1*	ENSMUSG00000071517	88
2210010C04Rik / RIKEN cDNA 2210010C04 gene	ENSMUSG00000029882	75
Gm2663	ENSMUSG00000096525	69
1810009J06Rik / RIKEN cDNA 1810009J06 gene	ENSMUSG00000094808	69
Klk14 / Q8CGR5 / Kallikrein-14 / Q9P0G3* / kallikrein related peptidase 14*	ENSMUSG00000044737	48
Klk13 / kallikrein related-peptidase 13 / Q9UKR3*	ENSMUSG00000054046	46
Klk11 / Q9QYN3 / Kallikrein-11 / Q9UBX7* / kallikrein related peptidase 11*	ENSMUSG00000067616	44
Klk15 / kallikrein related peptidase 15 / Q9H2R5*	ENSMUSG00000055193	43
Klk8 / Q61955 / Kallikrein-8 / O60259* / kallikrein related peptidase 8*	ENSMUSG00000064023	43
Klk9 / Q9UKQ9* / AC011473.4* / kallikrein related peptidase 9*	ENSMUSG00000047884	43
Klk6 / kallikrein related peptidase 6 / Q92876*	ENSMUSG00000050063	41
Gm4744	ENSMUSG00000063252	41

Protein motifs (from Interpro)

Interpro ID	Name
IPR001254	Serine proteases, trypsin domain
IPR001314	Peptidase S1A, chymotrypsin family
IPR009003	Peptidase S1, PA clan
IPR018114	Serine proteases, trypsin family, histidine active site
IPR033116	Serine proteases, trypsin family, serine active site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006508	proteolysis	IBA
biological_process	GO:0007584	response to nutrient	IEA
biological_process	GO:0007586	digestion	IEA
biological_process	GO:0010033	response to organic substance	IEA
biological_process	GO:0030574	collagen catabolic process	ISO
biological_process	GO:0031000	response to caffeine	IEA
biological_process	GO:0035094	response to nicotine	IEA
cellular_component	GO:0005576	extracellular region	ISO
cellular_component	GO:0005615	extracellular space	ISS
molecular_function	GO:0004252	serine-type endopeptidase activity	IBA
molecular_function	GO:0005509	calcium ion binding	ISS
molecular_function	GO:0008233	peptidase activity	IEA
molecular_function	GO:0008236	serine-type peptidase activity	IEA
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Collagen degradation

Activation of Matrix Metalloproteinases

Cobalamin (Cbl, vitamin B12) transport and metabolism

Neutrophil degranulation

Antimicrobial peptides

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr