ENSMUSG00000036938


Mus musculus

Features
Gene ID: ENSMUSG00000036938
  
Biological name :Try5
  
Synonyms : Try5
  
Possible biological names infered from orthology : P07477 / P07478 / P35030 / PRSS1 / PRSS2 / PRSS3 / serine protease 1 / serine protease 2 / serine protease 3
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B1
Gene start: 41311233
Gene end: 41316841
  
Corresponding Affymetrix probe sets: 10544333 (MoGene1.0st)   1415954_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064498
Ensembl peptide - ENSMUSP00000133640
NCBI entrez gene - 103964     See in Manteia.
MGI - MGI:102756
RefSeq - NM_001003405
RefSeq Peptide - NP_001003405
swissprot - G3UXD0
swissprot - Q9QUK9
Ensembl - ENSMUSG00000036938
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prss1ENSDARG00000042993Danio rerio
 ENSGALG00000027291Gallus gallus
 ENSGALG00000030650Gallus gallus
 ENSGALG00000040609Gallus gallus
 PRSS2ENSGALG00000032796Gallus gallus
 PRSS1ENSG00000204983Homo sapiens
 PRSS2ENSG00000275896Homo sapiens
 PRSS3ENSG00000010438Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Try4 / trypsin 4 / PRSS3* / PRSS1* / PRSS2* / P35030* / P07478* / P07477* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000005410698
Gm10334 / PRSS1* / PRSS2* / PRSS3* / P07477* / P07478* / P35030* / serine protease 2* / serine protease 3* / serine protease 1*ENSMUSG0000007151793
Gm5771 / PRSS1* / PRSS2* / PRSS3* / P07477* / P07478* / P35030* / serine protease 2* / serine protease 3* / serine protease 1*ENSMUSG0000005811993
Prss1 / PRSS2* / PRSS3* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000006275193
Prss3 / PRSS2* / PRSS1* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000007151993
Try10 / trypsin 10 / PRSS3* / PRSS1* / PRSS2* / P35030* / P07478* / P07477* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000007152192
Prss2 / P07146 / protease, serine 2 / PRSS1* / PRSS3* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000005716390
2210010C04Rik / RIKEN cDNA 2210010C04 geneENSMUSG0000002988277
1810009J06Rik / RIKEN cDNA 1810009J06 geneENSMUSG0000009480867
Gm2663ENSMUSG0000009652567
Klk14 / Q8CGR5 / Kallikrein-14 / Q9P0G3* / kallikrein related peptidase 14*ENSMUSG0000004473747
Klk13 / kallikrein related-peptidase 13 / Q9UKR3*ENSMUSG0000005404646
Klk11 / Q9QYN3 / Kallikrein-11 / Q9UBX7* / kallikrein related peptidase 11*ENSMUSG0000006761644
Klk9 / Q9UKQ9* / AC011473.4* / kallikrein related peptidase 9*ENSMUSG0000004788444
Klk15 / kallikrein related peptidase 15 / Q9H2R5*ENSMUSG0000005519343
Klk8 / Q61955 / Kallikrein-8 / O60259* / kallikrein related peptidase 8*ENSMUSG0000006402343
Gm4744ENSMUSG0000006325241
Klk6 / kallikrein related peptidase 6 / Q92876*ENSMUSG0000005006341


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007586 digestion IBA
 cellular_componentGO:0005615 extracellular space ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity ISO
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Activation of Matrix Metalloproteinases
Cobalamin (Cbl, vitamin B12) transport and metabolism
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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