ENSDARG00000043848


Danio rerio

Features
Gene ID: ENSDARG00000043848
  
Biological name :sod1
  
Synonyms : O73872 / sod1 / superoxide dismutase 1, soluble
  
Possible biological names infered from orthology : P00441 / P08228 / superoxide dismutase 1 / Superoxide dismutase [Cu-Zn]
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 25694395
Gene end: 25699454
  
Corresponding Affymetrix probe sets: Dr.20938.1.S1_at (Zebrafish Array)   NM_131294_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064375
NCBI entrez gene - 30553     See in Manteia.
RefSeq - NM_131294
RefSeq Peptide - NP_571369
swissprot - B2GRH9
swissprot - O73872
ZFIN ID - ZDB-GENE-990415-258
Ensembl - ENSDARG00000043848
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOD1ENSGALG00000015844Gallus gallus
 SOD1ENSG00000142168Homo sapiens
 Sod1ENSMUSG00000022982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ccs / copper chaperone for superoxide dismutase / O14618*ENSDARG0000011624647
ccs / copper chaperone for superoxide dismutase / O14618* / Q9WU84*ENSDARG0000009200347
sod3b / superoxide dismutase 3, extracellular b / SOD3* / P08294* / O09164* / superoxide dismutase 3* / superoxide dismutase 3, extracellular*ENSDARG0000007918337
sod3a / superoxide dismutase 3, extracellular a / SOD3* / P08294* / O09164* / superoxide dismutase 3* / superoxide dismutase 3, extracellular*ENSDARG0000007016836


Protein motifs (from Interpro)
Interpro ID Name
 IPR001424  Superoxide dismutase, copper/zinc binding domain
 IPR018152  Superoxide dismutase, copper/zinc, binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006801 superoxide metabolic process IEA
 biological_processGO:0009410 response to xenobiotic stimulus IDA
 biological_processGO:0010038 response to metal ion IDA
 biological_processGO:0019430 removal of superoxide radicals IEA
 biological_processGO:0051597 response to methylmercury IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070050 neuron cellular homeostasis IMP
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004784 superoxide dismutase activity IEA
 molecular_functionGO:0005507 copper ion binding IBA
 molecular_functionGO:0008270 zinc ion binding IBA
 molecular_functionGO:0016209 antioxidant activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001115 trunk trunk neuromuscular junction morphology , abnormal
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 ZFA:0009052 motor neuron motor neuron axon decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043848 sod1 / O73872 / superoxide dismutase 1, soluble / P00441* / P08228* / superoxide dismutase 1* / Superoxide dismutase [Cu-Zn] *  / complex / reaction
 ENSDARG00000092003 ccs / copper chaperone for superoxide dismutase / O14618* / Q9WU84*  / reaction / complex






 

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