ENSDARG00000051923


Danio rerio

Features
Gene ID: ENSDARG00000051923
  
Biological name :ccnb1
  
Synonyms : ccnb1 / cyclin B1
  
Possible biological names infered from orthology : G2/mitotic-specific cyclin-B1 / P14635 / P24860
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 54711027
Gene end: 54714789
  
Corresponding Affymetrix probe sets: Dr.25226.1.S1_s_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000063356
Ensembl peptide - ENSDARP00000123795
Ensembl peptide - ENSDARP00000123945
Ensembl peptide - ENSDARP00000124847
swissprot - F8W257
swissprot - F8W498
swissprot - F8W534
swissprot - Q7ZU21
ZFIN ID - ZDB-GENE-000406-10
Ensembl - ENSDARG00000051923
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCNB1ENSG00000134057Homo sapiens
 Ccnb1ENSMUSG00000041431Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ccnb2 / cyclin B2 / O95067* / P30276* / G2/mitotic-specific cyclin-B2 *ENSDARG0000003618048
ccna1 / cyclin A1 / P78396* / Q61456*ENSDARG0000004323627
ccna2 / cyclin A2 / P20248*ENSDARG0000001109427
ccnb3 / cyclin B3 / Q8WWL7*ENSDARG0000003485526
ccne2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *ENSDARG0000009852920
ccne1 / cyclin E1 / P24864* / Q61457* / G1/S-specific cyclin-E1 *ENSDARG0000009862219
ccnd2a / cyclin D2, a / CCND2* / P30279* / P30280* / cyclin D2* / G1/S-specific cyclin-D2 *ENSDARG0000005174814
FQ311924.1 / CCNO* / P22674* / cyclin O*ENSDARG0000009954214
ccnd3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *ENSDARG0000002739113
ccnd2b / cyclin D2, b / CCND2* / P30279* / P30280* / cyclin D2* / G1/S-specific cyclin-D2 *ENSDARG0000007040812
ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *ENSDARG0000010163712
si:ch211-152f23.5ENSDARG0000001974111


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001556 oocyte maturation IDA
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
APC/C:Cdc20 mediated degradation of Cyclin B
Regulation of APC/C activators between G1/S and early anaphase
Phosphorylation of the APC/C
Phosphorylation of Emi1
Condensation of Prophase Chromosomes
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly
Depolymerisation of the Nuclear Lamina
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Mitotic Prophase
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Transcriptional regulation by RUNX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
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 ZFA:0001114 head head flat , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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