ENSDARG00000043236


Danio rerio

Features
Gene ID: ENSDARG00000043236
  
Biological name :ccna1
  
Synonyms : ccna1 / cyclin A1
  
Possible biological names infered from orthology : P78396 / Q61456
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 34905980
Gene end: 34916208
  
Corresponding Affymetrix probe sets: Dr.5555.1.S1_at (Zebrafish Array)   NM_212818_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115807
Ensembl peptide - ENSDARP00000149259
Ensembl peptide - ENSDARP00000020968
NCBI entrez gene - 404206     See in Manteia.
RefSeq - NM_212818
RefSeq Peptide - NP_997983
swissprot - E9QJ66
swissprot - F1QGH4
ZFIN ID - ZDB-GENE-040311-2
Ensembl - ENSDARG00000043236
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCNA1ENSGALG00000017052Gallus gallus
 CCNA1ENSG00000133101Homo sapiens
 Ccna1ENSMUSG00000027793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ccna2 / cyclin A2 / P20248*ENSDARG0000001109448
ccnb2 / cyclin B2 / O95067* / P30276* / G2/mitotic-specific cyclin-B2 *ENSDARG0000003618029
ccnb1 / cyclin B1 / P14635* / P24860* / G2/mitotic-specific cyclin-B1 *ENSDARG0000005192327
ccnb3 / cyclin B3 / Q8WWL7*ENSDARG0000003485526
ccne1 / cyclin E1 / P24864* / Q61457* / G1/S-specific cyclin-E1 *ENSDARG0000009862218
ccne2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *ENSDARG0000009852918
FQ311924.1 / CCNO* / P22674* / cyclin O*ENSDARG0000009954217
ccnd2b / cyclin D2, b / CCND2* / P30279* / P30280* / cyclin D2* / G1/S-specific cyclin-D2 *ENSDARG0000007040815
ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *ENSDARG0000010163715
ccnd2a / cyclin D2, a / CCND2* / P30279* / P30280* / cyclin D2* / G1/S-specific cyclin-D2 *ENSDARG0000005174814
ccnd3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *ENSDARG0000002739113
si:ch211-152f23.5ENSDARG0000001974113


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Regulation of APC/C activators between G1/S and early anaphase
SCF(Skp2)-mediated degradation of p27/p21
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
Ub-specific processing proteases
Processing of DNA double-strand break ends
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
G2 Phase
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Cyclin A/B1/B2 associated events during G2/M transition
p53-Dependent G1 DNA Damage Response
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000015315 psmc5 / proteasome 26S subunit, ATPase 5 / P62195* / P62196* / protease (prosome, macropain) 26S subunit, ATPase 5*  / complex
 ENSDARG00000002591 ruvbl1 / RuvB-like AAA ATPase 1 / P60122* / Q9Y265* / RuvB-like protein 1*  / complex






 

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