ENSGALG00000017052


Gallus gallus

Features
Gene ID: ENSGALG00000017052
  
Biological name :CCNA1
  
Synonyms : CCNA1 / cyclin A1
  
Possible biological names infered from orthology : P78396 / Q61456
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 172568581
Gene end: 172574262
  
Corresponding Affymetrix probe sets: GgaAffx.10919.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027497
NCBI entrez gene - 418901     See in Manteia.
RefSeq - XM_004938747
RefSeq - XM_417097
RefSeq - XM_004938748
RefSeq - XM_015278427
swissprot - F1P4N0
Ensembl - ENSGALG00000017052
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccna1ENSDARG00000043236Danio rerio
 CCNA1ENSG00000133101Homo sapiens
 Ccna1ENSMUSG00000027793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCNA2 / cyclin-A2 / P20248* / P51943*ENSGALG0000001188147
CCNB2 / P29332 / G2/mitotic-specific cyclin-B2 / O95067* / P30276* / cyclin B2*ENSGALG0000000416126
CCNB3 / Q8WWL7* / cyclin B3*ENSGALG0000002581026
CCNE2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *ENSGALG0000004079419
CCNE1 / G1/S-specific cyclin-E1 / P24864* / Q61457* / cyclin E1*ENSGALG0000000449419
CCNO / cyclin O / P0C242* / P22674*ENSGALG0000002859518
CCND3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *ENSGALG0000000348517
CCND2 / P49706 / G1/S-specific cyclin-D2 / P30279* / P30280* / cyclin D2*ENSGALG0000001728314
CCND1 / G1/S-specific cyclin-D1 / P24385* / P25322* / cyclin D1*ENSGALG0000000755514


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR032447  Cyclin-A, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0097123 cyclin A1-CDK2 complex IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Regulation of APC/C activators between G1/S and early anaphase
SCF(Skp2)-mediated degradation of p27/p21
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
Ub-specific processing proteases
Processing of DNA double-strand break ends
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Degradation
G2 Phase
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Cyclin A/B1/B2 associated events during G2/M transition
p53-Dependent G1 DNA Damage Response
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000349 PSMC5 / proteasome 26S subunit, ATPase 5 / P62195* / P62196* / protease (prosome, macropain) 26S subunit, ATPase 5*  / complex
 ENSGALG00000005931 RUVBL1 / ruvB-like 1 / Q9Y265* / P60122* / RuvB-like protein 1* / RuvB like AAA ATPase 1*  / complex






 

1 s.

 
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contact: otassy@igbmc.fr