ENSGALG00000011881


Gallus gallus

Features
Gene ID: ENSGALG00000011881
  
Biological name :CCNA2
  
Synonyms : CCNA2 / cyclin-A2
  
Possible biological names infered from orthology : P20248 / P51943
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 54290252
Gene end: 54295395
  
Corresponding Affymetrix probe sets: Gga.4129.1.S1_at (Chicken Array)   Gga.4129.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019361
NCBI entrez gene - 396172     See in Manteia.
RefSeq - NM_205244
RefSeq Peptide - NP_990575
swissprot - F1NJI2
Ensembl - ENSGALG00000011881
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccna2ENSDARG00000011094Danio rerio
 CCNA2ENSG00000145386Homo sapiens
 Ccna2ENSMUSG00000027715Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCNA1 / cyclin A1 / P78396* / Q61456*ENSGALG0000001705248
CCNB2 / P29332 / G2/mitotic-specific cyclin-B2 / O95067* / P30276* / cyclin B2*ENSGALG0000000416128
CCNB3 / Q8WWL7* / cyclin B3*ENSGALG0000002581023
CCNE1 / G1/S-specific cyclin-E1 / P24864* / Q61457* / cyclin E1*ENSGALG0000000449419
CCNE2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *ENSGALG0000004079418
CCND3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *ENSGALG0000000348517
CCNO / cyclin O / P0C242* / P22674*ENSGALG0000002859516
CCND2 / P49706 / G1/S-specific cyclin-D2 / P30279* / P30280* / cyclin D2*ENSGALG0000001728315
CCND1 / G1/S-specific cyclin-D1 / P24385* / P25322* / cyclin D1*ENSGALG0000000755514


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR032447  Cyclin-A, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IEA
 biological_processGO:0007265 Ras protein signal transduction IEA
 biological_processGO:0016572 histone phosphorylation IEA
 biological_processGO:0044843 cell cycle G1/S phase transition IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IEA
 cellular_componentGO:0001939 female pronucleus IEA
 cellular_componentGO:0001940 male pronucleus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0097124 cyclin A2-CDK2 complex IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0097472 cyclin-dependent protein kinase activity IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Regulation of APC/C activators between G1/S and early anaphase
SCF(Skp2)-mediated degradation of p27/p21
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
Ub-specific processing proteases
Processing of DNA double-strand break ends
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Degradation
G2 Phase
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Cyclin A/B1/B2 associated events during G2/M transition
p53-Dependent G1 DNA Damage Response
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr