ENSGALG00000007555


Gallus gallus

Features
Gene ID: ENSGALG00000007555
  
Biological name :CCND1
  
Synonyms : CCND1 / G1/S-specific cyclin-D1
  
Possible biological names infered from orthology : cyclin D1 / P24385 / P25322
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 17525970
Gene end: 17539612
  
Corresponding Affymetrix probe sets: Gga.3039.1.S1_at (Chicken Array)   GgaAffx.22277.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012203
Ensembl peptide - ENSGALP00000062973
Ensembl peptide - ENSGALP00000059934
Ensembl peptide - ENSGALP00000046707
NCBI entrez gene - 396341     See in Manteia.
RefSeq - NM_205381
RefSeq Peptide - NP_990712
swissprot - A0A1L1RVV4
swissprot - A0A1L1RME1
swissprot - A0A1D5P213
swissprot - F1NS84
Ensembl - ENSGALG00000007555
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccnd1ENSDARG00000101637Danio rerio
 CCND1ENSG00000110092Homo sapiens
 Ccnd1ENSMUSG00000070348Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCND2 / P49706 / G1/S-specific cyclin-D2 / P30279* / P30280* / cyclin D2*ENSGALG0000001728364
CCND3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *ENSGALG0000000348554
CCNE1 / G1/S-specific cyclin-E1 / P24864* / Q61457* / cyclin E1*ENSGALG0000000449423
CCNE2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *ENSGALG0000004079422
CCNA2 / cyclin-A2 / P20248* / P51943*ENSGALG0000001188119
CCNA1 / cyclin A1 / P78396* / Q61456*ENSGALG0000001705219
CCNB3 / Q8WWL7* / cyclin B3*ENSGALG0000002581018
CCNO / cyclin O / P0C242* / P22674*ENSGALG0000002859517
CCNB2 / P29332 / G2/mitotic-specific cyclin-B2 / O95067* / P30276* / cyclin B2*ENSGALG0000000416116


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR015451  Cyclin D


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000320 re-entry into mitotic cell cycle IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0010971 positive regulation of G2/M transition of mitotic cell cycle IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030857 negative regulation of epithelial cell differentiation IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0031571 mitotic G1 DNA damage checkpoint IEA
 biological_processGO:0033598 mammary gland epithelial cell proliferation IEA
 biological_processGO:0033601 positive regulation of mammary gland epithelial cell proliferation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0044321 response to leptin IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0070141 response to UV-A IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:0071310 cellular response to organic substance IEA
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0070064 proline-rich region binding IEA


Pathways (from Reactome)
Pathway description
Ubiquitin-dependent degradation of Cyclin D1
Cyclin D associated events in G1
Regulation of RUNX1 Expression and Activity
RUNX3 regulates p14-ARF


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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