ENSDARG00000011094


Danio rerio

Features
Gene ID: ENSDARG00000011094
  
Biological name :ccna2
  
Synonyms : ccna2 / cyclin A2
  
Possible biological names infered from orthology : P20248 / P51943
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 46354648
Gene end: 46374870
  
Corresponding Affymetrix probe sets: Dr.25190.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000029094
Ensembl peptide - ENSDARP00000146428
Ensembl peptide - ENSDARP00000156205
NCBI entrez gene - 192295     See in Manteia.
swissprot - Q6NV43
ZFIN ID - ZDB-GENE-020418-1
Ensembl - ENSDARG00000011094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCNA2ENSGALG00000011881Gallus gallus
 CCNA2ENSG00000145386Homo sapiens
 Ccna2ENSMUSG00000027715Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ccna1 / cyclin A1 / P78396* / Q61456*ENSDARG0000004323641
ccnb3 / cyclin B3 / Q8WWL7*ENSDARG0000003485524
ccnb2 / cyclin B2 / O95067* / P30276* / G2/mitotic-specific cyclin-B2 *ENSDARG0000003618024
ccnb1 / cyclin B1 / P14635* / P24860* / G2/mitotic-specific cyclin-B1 *ENSDARG0000005192323
ccne1 / cyclin E1 / P24864* / Q61457* / G1/S-specific cyclin-E1 *ENSDARG0000009862219
ccne2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *ENSDARG0000009852918
FQ311924.1 / CCNO* / P22674* / cyclin O*ENSDARG0000009954216
ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *ENSDARG0000010163714
ccnd2a / cyclin D2, a / CCND2* / P30279* / P30280* / cyclin D2* / G1/S-specific cyclin-D2 *ENSDARG0000005174813
ccnd2b / cyclin D2, b / CCND2* / P30279* / P30280* / cyclin D2* / G1/S-specific cyclin-D2 *ENSDARG0000007040813
ccnd3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *ENSDARG0000002739112
si:ch211-152f23.5ENSDARG0000001974111


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR032447  Cyclin-A, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Regulation of APC/C activators between G1/S and early anaphase
SCF(Skp2)-mediated degradation of p27/p21
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
Ub-specific processing proteases
Processing of DNA double-strand break ends
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
G2 Phase
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Cyclin A/B1/B2 associated events during G2/M transition
p53-Dependent G1 DNA Damage Response
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
Show

 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
Show

 ZFA:0000152 retina retina quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001114 head head decreased width , abnormal
head pointed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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