ENSDARG00000052816


Danio rerio

Features
Gene ID: ENSDARG00000052816
  
Biological name :shmt1
  
Synonyms : serine hydroxymethyltransferase 1 (soluble) / shmt1
  
Possible biological names infered from orthology : P34896 / P50431 / serine hydroxymethyltransferase 1
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 40260929
Gene end: 40276071
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000069223
Ensembl peptide - ENSDARP00000123687
Ensembl peptide - ENSDARP00000121832
NCBI entrez gene - 394021     See in Manteia.
RefSeq - NM_201046
RefSeq Peptide - NP_957340
swissprot - E9QEK5
swissprot - E9QBE1
swissprot - Q6NYR0
ZFIN ID - ZDB-GENE-040426-1558
Ensembl - ENSDARG00000052816
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SHMT1ENSGALG00000005046Gallus gallus
 SHMT1ENSG00000176974Homo sapiens
 Shmt1ENSMUSG00000020534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
shmt2 / serine hydroxymethyltransferase 2 (mitochondrial) / P34897* / serine hydroxymethyltransferase 2*ENSDARG0000010441462


Protein motifs (from Interpro)
Interpro ID Name
 IPR001085  Serine hydroxymethyltransferase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR019798  Serine hydroxymethyltransferase, pyridoxal phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0019264 glycine biosynthetic process from serine IEA
 biological_processGO:0035999 tetrahydrofolate interconversion IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004372 glycine hydroxymethyltransferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines
Carnitine synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052816 shmt1 / serine hydroxymethyltransferase 1 (soluble) / P34896* / P50431* / serine hydroxymethyltransferase 1*  / complex






 

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contact: otassy@igbmc.fr