ENSDARG00000104414


Danio rerio

Features
Gene ID: ENSDARG00000104414
  
Biological name :shmt2
  
Synonyms : serine hydroxymethyltransferase 2 (mitochondrial) / shmt2
  
Possible biological names infered from orthology : P34897 / serine hydroxymethyltransferase 2
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 59176470
Gene end: 59230818
  
Corresponding Affymetrix probe sets: Dr.12553.1.S1_at (Zebrafish Array)   Dr.24150.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000132340
NCBI entrez gene - 100144628     See in Manteia.
RefSeq - NM_001123374
RefSeq Peptide - NP_001116846
swissprot - A0A0R4IBM1
swissprot - A9LDD9
ZFIN ID - ZDB-GENE-071213-1
Ensembl - ENSDARG00000104414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SHMT2ENSG00000182199Homo sapiens
 Shmt2ENSMUSG00000025403Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
shmt1 / serine hydroxymethyltransferase 1 (soluble) / P34896* / P50431* / serine hydroxymethyltransferase 1*ENSDARG0000005281660


Protein motifs (from Interpro)
Interpro ID Name
 IPR001085  Serine hydroxymethyltransferase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019264 glycine biosynthetic process from serine IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0035999 tetrahydrofolate interconversion IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004372 glycine hydroxymethyltransferase activity IDA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IDA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000104414 shmt2 / serine hydroxymethyltransferase 2 (mitochondrial) / P34897* / serine hydroxymethyltransferase 2*  / complex






 

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contact: otassy@igbmc.fr