ENSDARG00000056331


Danio rerio

Features
Gene ID: ENSDARG00000056331
  
Biological name :ahcyl1
  
Synonyms : adenosylhomocysteinase-like 1 / ahcyl1
  
Possible biological names infered from orthology : Mus musculus S-adenosylhomocysteine hydrolase-like 1 (Ahcyl1), transcript variant 5, mRNA. / O43865 / Q80SW1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 24971890
Gene end: 25011157
  
Corresponding Affymetrix probe sets: Dr.5873.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073253
Ensembl peptide - ENSDARP00000073256
NCBI entrez gene - 798918     See in Manteia.
RefSeq - NM_201293
RefSeq Peptide - NP_958450
swissprot - A5PMG4
swissprot - A5PMG3
ZFIN ID - ZDB-GENE-021206-7
Ensembl - ENSDARG00000056331
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AHCYL1ENSGALG00000000329Gallus gallus
 AHCYL1ENSG00000168710Homo sapiens
 Ahcyl1ENSMUSG00000027893Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ahcyl2 / adenosylhomocysteinase-like 2 / Q68FL4* / Q96HN2* / S-adenosylhomocysteine hydrolase-like 2*ENSDARG0000003934381
zgc:158222 / Q96HN2* / Q68FL4* / AHCYL2* / adenosylhomocysteinase like 2* / S-adenosylhomocysteine hydrolase-like 2*ENSDARG0000005187369
ahcy / adenosylhomocysteinase / Gm4737* / P23526* / P50247* / predicted gene 4737*ENSDARG0000000519140


Protein motifs (from Interpro)
Interpro ID Name
 IPR000043  Adenosylhomocysteinase-like
 IPR015878  S-adenosyl-L-homocysteine hydrolase, NAD binding domain
 IPR016040  NAD(P)-binding domain
 IPR020082  S-adenosyl-L-homocysteine hydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0033353 S-adenosylmethionine cycle IBA
 biological_processGO:0048598 embryonic morphogenesis IMP
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004013 adenosylhomocysteinase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain necrotic , abnormal
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 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
whole organism increased curvature , abnormal
Show

 ZFA:0001117 post-vent region post-vent region distended , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014655 itpr1a / inositol 1,4,5-trisphosphate receptor, type 1a / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*  / complex / reaction






 

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