ENSDARG00000059236


Danio rerio

Features
Gene ID: ENSDARG00000059236
  
Biological name :ptger4a
  
Synonyms : prostaglandin E receptor 4 (subtype EP4) a / ptger4a
  
Possible biological names infered from orthology : P32240 / P35408 / prostaglandin E receptor 4 / prostaglandin E receptor 4 (subtype EP4) / PTGER4
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 902750
Gene end: 912821
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000092384
NCBI entrez gene - 562469     See in Manteia.
RefSeq - NM_001039629
RefSeq Peptide - NP_001034718
swissprot - F1Q955
ZFIN ID - ZDB-GENE-060222-1
Ensembl - ENSDARG00000059236
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGER4ENSGALG00000014824Gallus gallus
 P35408ENSG00000171522Homo sapiens
 P32240ENSMUSG00000039942Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptger4b / prostaglandin E receptor 4 (subtype EP4) b / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000003541565
ptger4c / prostaglandin E receptor 4 (subtype EP4) cENSDARG0000007990742
ptgir / prostaglandin I2 receptor / P43119* / P43252* / Prostacyclin receptor *ENSDARG0000003827830
ptger2b / prostaglandin E receptor 2b (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000003703328
ptger2a / prostaglandin E receptor 2a (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000001143426
ptger3 / prostaglandin E receptor 3 (subtype EP3) / P43115* / prostaglandin E receptor 3*ENSDARG0000005578124
ptger1a / prostaglandin E receptor 1a (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000007860522
ptger1c / prostaglandin E receptor 1c (subtype EP1)ENSDARG0000007860221
ptger1b / prostaglandin E receptor 1b (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000010484721
ptgfr / prostaglandin F receptor (FP) / P43088* / P43117* / prostaglandin F receptor*ENSDARG0000007401620
tbxa2r / thromboxane A2 receptor / P21731*ENSDARG0000010471712


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001244  Prostaglandin DP receptor
 IPR001758  Prostanoid EP4 receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0033077 T cell differentiation in thymus IMP
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:1990402 embryonic liver development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004955 prostaglandin receptor activity IEA
 molecular_functionGO:0004957 prostaglandin E receptor activity IDA


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle has fewer parts of type Kupffers vesicle motile cilium, abnormal
Kupffers vesicle motile cilium decreased length , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
brain ventricular system edematous , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle has extra parts of type otolith , abnormal
Show

 ZFA:0000092 axis axis decreased length , abnormal
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 ZFA:0000114 heart heart bilateral symmetry , abnormal
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 ZFA:0000123 liver liver amount , ameliorated
liver size , ameliorated
liver decreased size , abnormal
liver decreased distribution , abnormal
Show

 ZFA:0000135 notochord notochord undulate , abnormal
notochord increased width , abnormal
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 ZFA:0000155 somite somite elongated , abnormal
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 ZFA:0000166 lateral crista lateral crista has fewer parts of type lateral crista kinocilium, abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
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 ZFA:0001114 head head position , abnormal
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 ZFA:0001115 trunk trunk curved ventral , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas amount , ameliorated
exocrine pancreas size , ameliorated
exocrine pancreas decreased size , abnormal
exocrine pancreas decreased distribution , abnormal
Show

 ZFA:0001622 pronephric distal early tubule pronephric distal early tubule increased size , abnormal
pronephric distal early tubule increased distribution , abnormal
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 ZFA:0001624 pronephric distal late tubule pronephric distal late tubule decreased size , abnormal
pronephric distal late tubule decreased distribution , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta morphology , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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