ENSDARG00000038278


Danio rerio

Features
Gene ID: ENSDARG00000038278
  
Biological name :ptgir
  
Synonyms : prostaglandin I2 receptor / ptgir
  
Possible biological names infered from orthology : P43119 / P43252 / Prostacyclin receptor
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 9117330
Gene end: 9184449
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128285
Ensembl peptide - ENSDARP00000157128
NCBI entrez gene - 561406     See in Manteia.
swissprot - E7FE45
ZFIN ID - ZDB-GENE-120511-1
Ensembl - ENSDARG00000038278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGIRENSG00000160013Homo sapiens
 PtgirENSMUSG00000043017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptger2a / prostaglandin E receptor 2a (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000001143436
ptger2b / prostaglandin E receptor 2b (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000003703335
ptger4a / prostaglandin E receptor 4 (subtype EP4) a / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000005923633
ptger4c / prostaglandin E receptor 4 (subtype EP4) cENSDARG0000007990733
ptger4b / prostaglandin E receptor 4 (subtype EP4) b / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000003541533
ptger1c / prostaglandin E receptor 1c (subtype EP1)ENSDARG0000007860224
ptger3 / prostaglandin E receptor 3 (subtype EP3) / P43115* / prostaglandin E receptor 3*ENSDARG0000005578124
ptger1b / prostaglandin E receptor 1b (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000010484722
ptger1a / prostaglandin E receptor 1a (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000007860521
ptgfr / prostaglandin F receptor (FP) / P43088* / P43117* / prostaglandin F receptor*ENSDARG0000007401621
tbxa2r / thromboxane A2 receptor / P21731*ENSDARG0000010471711


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000370  Prostacyclin (prostanoid IP) receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0016501 prostacyclin receptor activity IDA


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
Prostacyclin signalling through prostacyclin receptor
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
heart edematous , ameliorated
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex






 

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