ENSDARG00000055781


Danio rerio

Features
Gene ID: ENSDARG00000055781
  
Biological name :ptger3
  
Synonyms : prostaglandin E receptor 3 (subtype EP3) / ptger3
  
Possible biological names infered from orthology : P43115 / prostaglandin E receptor 3
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 37308716
Gene end: 37311049
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000079933
NCBI entrez gene - 100000544     See in Manteia.
swissprot - E7FD73
ZFIN ID - ZDB-GENE-120508-5
Ensembl - ENSDARG00000055781
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGER3ENSGALG00000023142Gallus gallus
 P43115ENSG00000050628Homo sapiens
 Ptger3ENSMUSG00000040016Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptger1b / prostaglandin E receptor 1b (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000010484729
ptgfr / prostaglandin F receptor (FP) / P43088* / P43117* / prostaglandin F receptor*ENSDARG0000007401628
ptger1a / prostaglandin E receptor 1a (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000007860528
ptger1c / prostaglandin E receptor 1c (subtype EP1)ENSDARG0000007860226
ptger4b / prostaglandin E receptor 4 (subtype EP4) b / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000003541525
ptger4a / prostaglandin E receptor 4 (subtype EP4) a / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000005923624
ptgir / prostaglandin I2 receptor / P43119* / P43252* / Prostacyclin receptor *ENSDARG0000003827822
ptger4c / prostaglandin E receptor 4 (subtype EP4) cENSDARG0000007990720
ptger2a / prostaglandin E receptor 2a (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000001143420
ptger2b / prostaglandin E receptor 2b (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000003703319
tbxa2r / thromboxane A2 receptor / P21731*ENSDARG0000010471713


Protein motifs (from Interpro)
Interpro ID Name
 IPR000265  Prostanoid EP3 receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001244  Prostaglandin DP receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0014827 intestine smooth muscle contraction IBA
 biological_processGO:0060455 negative regulation of gastric acid secretion IBA
 biological_processGO:1903670 regulation of sprouting angiogenesis IGI
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004955 prostaglandin receptor activity IEA
 molecular_functionGO:0004957 prostaglandin E receptor activity IDA


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , ameliorated
intersegmental vessel hypoplastic , abnormal
intersegmental vessel sprouting angiogenesis occurrence , ameliorated
intersegmental vessel sprouting angiogenesis decreased occurrence , abnormal
intersegmental vessel endothelial cell decreased amount , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature amount , ameliorated
trunk vasculature increased amount , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel hypoplastic , abnormal
dorsal longitudinal anastomotic vessel morphology , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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