ENSG00000050628


Homo sapiens

Features
Gene ID: ENSG00000050628
  
Biological name :PTGER3
  
Synonyms : P43115 / prostaglandin E receptor 3 / PTGER3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p31.1
Gene start: 70852353
Gene end: 71047808
  
Corresponding Affymetrix probe sets: 208169_s_at (Human Genome U133 Plus 2.0 Array)   210374_x_at (Human Genome U133 Plus 2.0 Array)   210375_at (Human Genome U133 Plus 2.0 Array)   210831_s_at (Human Genome U133 Plus 2.0 Array)   210832_x_at (Human Genome U133 Plus 2.0 Array)   210833_at (Human Genome U133 Plus 2.0 Array)   210834_s_at (Human Genome U133 Plus 2.0 Array)   211265_at (Human Genome U133 Plus 2.0 Array)   211909_x_at (Human Genome U133 Plus 2.0 Array)   213933_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423561
Ensembl peptide - ENSP00000421583
Ensembl peptide - ENSP00000424340
Ensembl peptide - ENSP00000486617
Ensembl peptide - ENSP00000280208
Ensembl peptide - ENSP00000302313
Ensembl peptide - ENSP00000346624
Ensembl peptide - ENSP00000349003
Ensembl peptide - ENSP00000359962
Ensembl peptide - ENSP00000359969
Ensembl peptide - ENSP00000359970
Ensembl peptide - ENSP00000418073
NCBI entrez gene - 5733     See in Manteia.
OMIM - 176806
RefSeq - XM_011541810
RefSeq - NM_001126044
RefSeq - NM_198714
RefSeq - NM_198715
RefSeq - NM_198716
RefSeq - NM_198717
RefSeq - NM_198718
RefSeq - NM_198719
RefSeq Peptide - NP_942009
RefSeq Peptide - NP_942010
RefSeq Peptide - NP_942011
RefSeq Peptide - NP_942012
RefSeq Peptide - NP_942008
RefSeq Peptide - NP_001119516
RefSeq Peptide - NP_942007
swissprot - O00325
swissprot - A0A0A0MRP3
swissprot - A0A0B4J204
swissprot - F8WAJ7
swissprot - P43115
Ensembl - ENSG00000050628
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptger3ENSDARG00000055781Danio rerio
 PTGER3ENSGALG00000023142Gallus gallus
 Ptger3ENSMUSG00000040016Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTGFR / P43088 / prostaglandin F receptorENSG0000012242028
P34995 / PTGER1 / prostaglandin E receptor 1ENSG0000016095128
P21731 / TBXA2R / thromboxane A2 receptorENSG0000000663828
PTGIR / P43119 / prostaglandin I2 receptorENSG0000016001323
P35408 / PTGER4 / prostaglandin E receptor 4ENSG0000017152222
P43116 / PTGER2 / prostaglandin E receptor 2ENSG0000012538422
PTGDR / Q13258 / prostaglandin D2 receptorENSG0000016822921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000265  Prostanoid EP3 receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001244  Prostaglandin DP receptor
 IPR001481  Prostanoid EP3 receptor, type 2
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008219 cell death TAS
 biological_processGO:0014827 intestine smooth muscle contraction IBA
 biological_processGO:0031622 positive regulation of fever generation ISS
 biological_processGO:0060455 negative regulation of gastric acid secretion IBA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004955 prostaglandin receptor activity IEA
 molecular_functionGO:0004957 prostaglandin E receptor activity TAS


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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