ENSG00000122420


Homo sapiens

Features
Gene ID: ENSG00000122420
  
Biological name :PTGFR
  
Synonyms : P43088 / prostaglandin F receptor / PTGFR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.1
Gene start: 78303884
Gene end: 78539749
  
Corresponding Affymetrix probe sets: 1555097_a_at (Human Genome U133 Plus 2.0 Array)   207177_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359792
Ensembl peptide - ENSP00000359793
Ensembl peptide - ENSP00000359794
Ensembl peptide - ENSP00000432599
NCBI entrez gene - 5737     See in Manteia.
OMIM - 600563
RefSeq - NM_000959
RefSeq - NM_001039585
RefSeq Peptide - NP_000950
RefSeq Peptide - NP_001034674
swissprot - P43088
swissprot - F2Z2Z6
Ensembl - ENSG00000122420
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptgfrENSDARG00000074016Danio rerio
 PTGFRENSGALG00000008901Gallus gallus
 PtgfrENSMUSG00000028036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P34995 / PTGER1 / prostaglandin E receptor 1ENSG0000016095137
P21731 / TBXA2R / thromboxane A2 receptorENSG0000000663834
P43115 / PTGER3 / prostaglandin E receptor 3ENSG0000005062833
P35408 / PTGER4 / prostaglandin E receptor 4ENSG0000017152223
PTGIR / P43119 / prostaglandin I2 receptorENSG0000016001323
P43116 / PTGER2 / prostaglandin E receptor 2ENSG0000012538421
PTGDR / Q13258 / prostaglandin D2 receptorENSG0000016822920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000141  Prostaglandin F receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007567 parturition TAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IDA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0071799 cellular response to prostaglandin D stimulus IMP
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004958 prostaglandin F receptor activity TAS


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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