ENSMUSG00000028036


Mus musculus

Features
Gene ID: ENSMUSG00000028036
  
Biological name :Ptgfr
  
Synonyms : P43117 / prostaglandin F receptor / Ptgfr
  
Possible biological names infered from orthology : P43088
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: H3
Gene start: 151796502
Gene end: 151837630
  
Corresponding Affymetrix probe sets: 10502805 (MoGene1.0st)   1420349_at (Mouse Genome 430 2.0 Array)   1440777_x_at (Mouse Genome 430 2.0 Array)   1446331_at (Mouse Genome 430 2.0 Array)   1449828_at (Mouse Genome 430 2.0 Array)   1453924_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029670
Ensembl peptide - ENSMUSP00000101732
NCBI entrez gene - 19220     See in Manteia.
MGI - MGI:97796
RefSeq - NM_008966
RefSeq Peptide - NP_032992
swissprot - P43117
swissprot - Q60I90
Ensembl - ENSMUSG00000028036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptgfrENSDARG00000074016Danio rerio
 PTGFRENSGALG00000008901Gallus gallus
 PTGFRENSG00000122420Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P35375 / Ptger1 / Prostaglandin E2 receptor EP1 subtype / P34995* / prostaglandin E receptor 1*ENSMUSG0000001946435
P30987 / Tbxa2r / thromboxane A2 receptor / P21731*ENSMUSG0000003488133
Ptger3 / prostaglandin E receptor 3 / P43115*ENSMUSG0000004001630
P32240 / Ptger4 / prostaglandin E receptor 4 (subtype EP4) / P35408* / prostaglandin E receptor 4*ENSMUSG0000003994223
Ptgir / P43252 / Prostacyclin receptor / P43119* / prostaglandin I2 receptor*ENSMUSG0000004301722
Ptger2 / Q62053 / prostaglandin E receptor 2 (subtype EP2) / P43116* / prostaglandin E receptor 2*ENSMUSG0000003775920
Ptgdr / P70263 / Prostaglandin D2 receptor / Q13258*ENSMUSG0000007148920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000141  Prostaglandin F receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001244  Prostaglandin DP receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0032355 response to estradiol IDA
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source ISO
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0071799 cellular response to prostaglandin D stimulus ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004955 prostaglandin receptor activity IEA
 molecular_functionGO:0004958 prostaglandin F receptor activity ISO


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001919 abnormal reproductive system physiology "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnfaip3tm1Ama/Tnfaip3tm1Ama
Genetic Background: Not Specified

 MP:0002783 abnormal ovarian secretion "malfunction of the production and/or release of hormones from ovarian tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnfaip3tm1Ama/Tnfaip3tm1Ama
Genetic Background: Not Specified

 MP:0012010 parturition failure "the process of labor and delivery in female animals does not initiate or complete" [MGI:csmith]
Show

Allelic Composition: Tnfaip3tm1Ama/Tnfaip3tm1Ama
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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