ENSG00000168229


Homo sapiens

Features
Gene ID: ENSG00000168229
  
Biological name :PTGDR
  
Synonyms : prostaglandin D2 receptor / PTGDR / Q13258
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q22.1
Gene start: 52267713
Gene end: 52276724
  
Corresponding Affymetrix probe sets: 215894_at (Human Genome U133 Plus 2.0 Array)   215937_at (Human Genome U133 Plus 2.0 Array)   234165_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303424
Ensembl peptide - ENSP00000452408
NCBI entrez gene - 5729     See in Manteia.
OMIM - 604687
RefSeq - XM_005267891
RefSeq - NM_000953
RefSeq - NM_001281469
RefSeq Peptide - NP_001268398
RefSeq Peptide - NP_000944
swissprot - Q13258
Ensembl - ENSG00000168229
  
Related genetic diseases (OMIM): 607277 - {Asthma, susceptibility to, 1}, 607277
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGDRENSGALG00000029768Gallus gallus
 PtgdrENSMUSG00000071489Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P43116 / PTGER2 / prostaglandin E receptor 2ENSG0000012538442
PTGIR / P43119 / prostaglandin I2 receptorENSG0000016001338
P35408 / PTGER4 / prostaglandin E receptor 4ENSG0000017152231
P21731 / TBXA2R / thromboxane A2 receptorENSG0000000663825
P43115 / PTGER3 / prostaglandin E receptor 3ENSG0000005062825
P34995 / PTGER1 / prostaglandin E receptor 1ENSG0000016095123
PTGFR / P43088 / prostaglandin F receptorENSG0000012242020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000376  Prostaglandin D receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0030238 male sex determination IEA
 biological_processGO:0030431 sleep IEA
 biological_processGO:0046085 adenosine metabolic process IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IBA
 biological_processGO:0071799 cellular response to prostaglandin D stimulus IEA
 biological_processGO:0097755 positive regulation of blood vessel diameter IBA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0001785 prostaglandin J receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004956 prostaglandin D receptor activity NAS
 molecular_functionGO:0004957 prostaglandin E receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr