ENSG00000125384


Homo sapiens

Features
Gene ID: ENSG00000125384
  
Biological name :PTGER2
  
Synonyms : P43116 / prostaglandin E receptor 2 / PTGER2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q22.1
Gene start: 52314305
Gene end: 52328606
  
Corresponding Affymetrix probe sets: 206631_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000245457
Ensembl peptide - ENSP00000450933
NCBI entrez gene - 5732     See in Manteia.
OMIM - 176804
RefSeq - NM_000956
RefSeq Peptide - NP_000947
swissprot - P43116
swissprot - G3V2Y6
Ensembl - ENSG00000125384
  
Related genetic diseases (OMIM): 208550 - {Asthma, aspirin-induced, susceptibility to}, 208550
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptger2aENSDARG00000011434Danio rerio
 ptger2bENSDARG00000037033Danio rerio
 PTGER2ENSGALG00000012396Gallus gallus
 Ptger2ENSMUSG00000037759Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTGDR / Q13258 / prostaglandin D2 receptorENSG0000016822942
PTGIR / P43119 / prostaglandin I2 receptorENSG0000016001340
P35408 / PTGER4 / prostaglandin E receptor 4ENSG0000017152232
P43115 / PTGER3 / prostaglandin E receptor 3ENSG0000005062826
P34995 / PTGER1 / prostaglandin E receptor 1ENSG0000016095125
P21731 / TBXA2R / thromboxane A2 receptorENSG0000000663824
PTGFR / P43088 / prostaglandin F receptorENSG0000012242021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001923  Prostanoid EP2 receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004957 prostaglandin E receptor activity TAS


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr