ENSDARG00000011434


Danio rerio

Features
Gene ID: ENSDARG00000011434
  
Biological name :ptger2a
  
Synonyms : prostaglandin E receptor 2a (subtype EP2) / ptger2a
  
Possible biological names infered from orthology : P43116 / prostaglandin E receptor 2 / prostaglandin E receptor 2 (subtype EP2) / PTGER2 / Q62053
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 14886828
Gene end: 14894144
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000015273
Ensembl peptide - ENSDARP00000112192
NCBI entrez gene - 393608     See in Manteia.
RefSeq - NM_200635
RefSeq Peptide - NP_956929
swissprot - Q2MV23
swissprot - Q6PFT8
ZFIN ID - ZDB-GENE-040426-1321
Ensembl - ENSDARG00000011434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGER2ENSGALG00000012396Gallus gallus
 P43116ENSG00000125384Homo sapiens
 Ptger2ENSMUSG00000037759Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptger2b / prostaglandin E receptor 2b (subtype EP2) / Q62053* / P43116* / PTGER2* / prostaglandin E receptor 2* / prostaglandin E receptor 2 (subtype EP2)*ENSDARG0000003703345
ptgir / prostaglandin I2 receptor / P43119* / P43252* / Prostacyclin receptor *ENSDARG0000003827836
ptger4a / prostaglandin E receptor 4 (subtype EP4) a / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000005923629
ptger4b / prostaglandin E receptor 4 (subtype EP4) b / P35408* / PTGER4* / P32240* / prostaglandin E receptor 4* / prostaglandin E receptor 4 (subtype EP4)*ENSDARG0000003541529
ptger4c / prostaglandin E receptor 4 (subtype EP4) cENSDARG0000007990727
ptger3 / prostaglandin E receptor 3 (subtype EP3) / P43115* / prostaglandin E receptor 3*ENSDARG0000005578122
ptger1b / prostaglandin E receptor 1b (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000010484722
ptger1a / prostaglandin E receptor 1a (subtype EP1) / P35375* / PTGER1* / P34995* / prostaglandin E receptor 1* / Prostaglandin E2 receptor EP1 subtype *ENSDARG0000007860521
ptger1c / prostaglandin E receptor 1c (subtype EP1)ENSDARG0000007860221
ptgfr / prostaglandin F receptor (FP) / P43088* / P43117* / prostaglandin F receptor*ENSDARG0000007401617
tbxa2r / thromboxane A2 receptor / P21731*ENSDARG000001047179


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000370  Prostacyclin (prostanoid IP) receptor
 IPR001923  Prostanoid EP2 receptor
 IPR008365  Prostanoid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IBA
 biological_processGO:1990402 embryonic liver development IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004957 prostaglandin E receptor activity IDA


Pathways (from Reactome)
Pathway description
Prostanoid ligand receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver amount , ameliorated
liver size , ameliorated
liver decreased size , abnormal
liver decreased distribution , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas amount , ameliorated
exocrine pancreas size , ameliorated
exocrine pancreas decreased size , abnormal
exocrine pancreas decreased distribution , abnormal
Show

 ZFA:0001622 pronephric distal early tubule pronephric distal early tubule increased size , abnormal
pronephric distal early tubule increased distribution , abnormal
pronephric distal early tubule spatial pattern , ameliorated
pronephric distal early tubule size , ameliorated
Show

 ZFA:0001624 pronephric distal late tubule pronephric distal late tubule decreased size , abnormal
pronephric distal late tubule decreased distribution , abnormal
pronephric distal late tubule spatial pattern , ameliorated
pronephric distal late tubule size , ameliorated
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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